Costs and quality of life in multiple sclerosis patients with spasticity
Article first published online: 18 MAY 2013
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Acta Neurologica Scandinavica
Volume 129, Issue 1, pages 13–20, January 2014
How to Cite
Costs and quality of life in multiple sclerosis patients with spasticity. Acta Neurol Scand 2014: 129: 13–20. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd., , .
- Issue published online: 3 DEC 2013
- Article first published online: 18 MAY 2013
- Manuscript Accepted: 3 APR 2013
- data collection;
- multiple sclerosis;
- muscle spasticity;
- quality of life
The resource use and health-related quality of life (HRQoL) of patients with multiple sclerosis (MS) spasticity are not well known. The purpose of this study was to obtain estimates of resource utilization, costs, and HRQoL, for patients with different levels of MS spasticity in southern Sweden.
Material and methods
Cross-sectional data on spasticity severity (using a Numerical Rating Scale, NRS), resource use and HRQoL (using EQ-5D) were collected using a patient questionnaire and chart review. Patients were recruited through a clinic in southern Sweden. The study reviews direct medical, direct non-medical and indirect costs.
Total costs were estimated to €114,293 per patient and year. Direct medical costs (€7898) accounted for 7% of total costs. Direct non-medical costs (€68,509) accounted for 60% of total costs. Total costs increased with severity of spasticity: for patients with severe spasticity, the total cost was 2.4 times greater than those for patients with mild spasticity. HRQoL decreased as spasticity increases.
The results of this study show that MS spasticity is associated with a substantial burden on society in terms of costs and HRQoL.