Brugada Phenocopy in a Patient with Pectus Excavatum: Systematic Review of the ECG Manifestations Associated with Pectus Excavatum

Authors


  • Statement: This manuscript is original; it has not and will not be submitted for publication elsewhere. Each author has contributed, read, and approved it for submission.

  • Disclosures: None

Address for correspondence: Dr. Adrian Baranchuk, M.D., FACC, Cardiac Electrophysiology and Pacing, Kingston General Hospital K7L 2V7, Queen's University, Ontario, Canada. Fax: +613-548-1387; E-mail: barancha@kgh.kari.net

Abstract

Brugada phenocopies (BrP) have emerged as new clinical entities that are etiologically distinct from true Brugada syndrome (BrS). BrP are characterized by an ECG pattern that is phenotypically identical to true BrS (type 1 or type 2); however, BrP are caused by various other factors such as mechanical mediastinal compression, myocardial ischemia, pericarditis, myocarditis, pulmonary embolism, and metabolic disturbances. We report a case of an electrocardiographic BrP in a patient with pectus excavatum deformity in the absence of true BrS using currently defined BrP diagnostic criteria. A systematic review of ECG manifestations associated with pectus excavatum is also discussed.

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