The study has been approved by the Institutional Ethic’s Comittee.
The clinical picture of juvenile parotitis in a prospective setup
Article first published online: 17 SEP 2012
© 2012 The Author(s)/Acta Pædiatrica © 2012 Foundation Acta Pædiatrica
Volume 102, Issue 2, pages 177–181, February 2013
How to Cite
Saarinen, R., Kolho, K.-L., Davidkin, I. and Pitkäranta, A. (2013), The clinical picture of juvenile parotitis in a prospective setup. Acta Paediatrica, 102: 177–181. doi: 10.1111/apa.12004
- Issue published online: 10 JAN 2013
- Article first published online: 17 SEP 2012
- Accepted manuscript online: 25 AUG 2012 09:55AM EST
- Received 1 June 2012; revised 13 August 2012; accepted 22 August 2012.
Aim: To characterize the features of juvenile parotitis in a prospective setup and epidemiology.
Methods: All children with parotitis admitted to Helsinki University Central Hospital 2005–2010 were recruited. Clinical characteristics, given treatment, outcome, blood leukocyte count, C-reactive protein, serum amylase and trypsinogen, SPINK-1 genotype and mumps antibodies were recorded. To map the epidemiology, a questionnaire was sent to 1000 randomly selected 13-year-old children.
Results: The prospective study included 41 children (aged ≤ 17) with acute parotitis, all in good general condition. Serum amylase, but not trypsinogen, was elevated in majority of the cases (79%) and C-reactive protein in 68%. Eleven (27%) children had an elevated blood leukocyte count. None had acute mumps. Most children recovered well, 51% being treated symptomatically only. Seven children were treated on ward. Seventeen (46%) children had recurrent symptoms. One child (2.4%) had SPINK P55S mutation. According to the epidemiological questionnaire, 1.1% of the respondents (8/728, response rate 73%) reported a verified episode(s) of parotitis.
Conclusion: Juvenile parotitis has a frequency close to 1%. In the majority, the general condition is good during the episode. Serum amylase serves as an additional marker for the disease. Parotitis has a tendency to recur in almost half of the cases.