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Severe infections caused by Panton–Valentine leukocidin-positive Staphylococcus aureus in infants: report of three cases and review of literature

Authors

  • Carlotta Montagnani,

    1. Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy
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  • Priscilla Cocchi,

    1. Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy
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  • Leila Bianchi,

    1. Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy
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  • Massimo Resti,

    1. Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy
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  • Maurizio de Martino,

    1. Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy
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  • Luisa Galli

    Corresponding author
    1. Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy
    • Correspondence

      Luisa Galli, M.D., Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Viale Pieraccini 24, I-50139, Florence, Italy. Tel: +39-055-566-2439; +39-055-418-211 |

      Fax: +39-055-4221012 |

      Email: luisa.galli@unifi.it

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Abstract

We report three cases of severe infections in infants caused by Panton–Valentine leukocidin positive Staphylococcus aureus and evolved with a positive outcome. The literature of Panton–Valentine leukocidin positive Staphylococcus aureus infections in infants is reviewed.

Conclusion

Our findings suggest that a prompt identification of Panton–Valentine leukocidin positive Staphylococcus aureus and an appropriate therapy can reduce mortality and long-term sequelae. Further research is needed to specify features of Panton–Valentine leukocidin positive Staphylococcus aureus infections in infants.

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