The Pediatric Symptom Checklist as screening tool for neurological and psychosocial problems in a paediatric cohort of patients with coeliac disease
Article first published online: 16 APR 2013
©2013 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd
Volume 102, Issue 7, pages e325–e328, July 2013
How to Cite
Terrone, G., Parente, I., Romano, A., Auricchio, R., Greco, L. and Del Giudice, E. (2013), The Pediatric Symptom Checklist as screening tool for neurological and psychosocial problems in a paediatric cohort of patients with coeliac disease. Acta Paediatrica, 102: e325–e328. doi: 10.1111/apa.12239
- Issue published online: 30 MAY 2013
- Article first published online: 16 APR 2013
- Accepted manuscript online: 21 MAR 2013 10:59AM EST
- Manuscript Accepted: 12 MAR 2013
- Manuscript Revised: 3 MAR 2013
- Manuscript Received: 23 JAN 2013
- Coeliac disease;
- Pediatric Symptom Checklist;
- Potential coeliac disease;
- Psychosocial problems
To screen for neurological and behavioural disorders in a paediatric cohort of patients with coeliac disease (CD) in order to detect possible differences related to compliance with gluten-free diet (GFD).
We recruited a cohort of 139 patients divided into three groups: A (40 patients with newly diagnosed CD), B (54 patients with CD in remission after GFD) and C (45 patients with potential CD). Patients first underwent a screening neurological visit, detecting signs associated with CD, and then were evaluated with Pediatric Symptom Checklist (PSC), a psychosocial screen for cognitive, emotional and behavioural problems.
In the group B as compared to group A, there was a statistically significant decrease (p < 0.05) in the incidence of chronic fatigue, headache and inattention. The same applied to patients compliant to GFD vs. non-compliant. Potential coeliacs turning into overt CD had a higher incidence of headache and inattention compared with potential coeliacs showing normal mucosa. The PSC mean score in group A was statistically higher than in group B.
Gluten-free diet had a positive impact on neuropsychiatric symptoms. We suggest the use of PSC in the routine follow-up of coeliacs in order to allow an early detection of psychosocial problems.