Both authors share first authorship.
Development of neuromotor functions in very low birth weight children from six to 10 years of age: patterns of change
Article first published online: 8 MAY 2013
©2013 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd
Volume 102, Issue 8, pages 809–814, August 2013
How to Cite
Natalucci, G., Schneider, M., Werner, H., Caflisch, J. A., Bucher, H. U., Jenni, O. G. and Latal, B. (2013), Development of neuromotor functions in very low birth weight children from six to 10 years of age: patterns of change. Acta Paediatrica, 102: 809–814. doi: 10.1111/apa.12271
- Issue published online: 21 JUN 2013
- Article first published online: 8 MAY 2013
- Accepted manuscript online: 19 APR 2013 05:06AM EST
- Manuscript Accepted: 15 APR 2013
- Manuscript Revised: 12 APR 2013
- Manuscript Received: 13 DEC 2012
- Swiss National Science Foundation. Grant Numbers: 32473B-129956, 33CM30-124101
- Motor overflow;
- Motor therapy;
- Neuromotor functions;
- School age;
- Very low birth weight;
- Zurich Neuromotor assessment
To assess patterns of change for different neuromotor functions in very low birth weight (VLBW) children during school age and to identify factors associated with improvement.
In a longitudinal study, we examined 65 prospectively enrolled VLBW children (38 female, 59%) without cerebral palsy at age six and 10 years. Measures included the evaluation of timed motor performance and motor overflow (MO) for the motor components of the Zurich Neuromotor Assessment (pure motor-, adaptive fine- and gross motor tasks, static balance) and a standardized neurological examination. Variables associated with improvement were assessed by multiple regression analyses.
Between six and 10 years, adaptive fine motor tasks (40% vs. 17% of children scoring below 10th percentile) and MO (77% vs. 55%) improved significantly (both p<0.01), while all other components remained stable (pure motor 23% vs. 25%, adaptive gross motor 26% vs. 34%, static balance 18% vs. 20%, respectively). Mild neurological abnormalities at 6 years of age were associated with less improvement.
Neuromotor functions improve in some children potentially reflecting catch up of maturational delay. However, the majority of neuromotor functions remain abnormal in a significant proportion of VLBW children.