Moderate acoustic changes can disrupt the sleep of very preterm infants in their incubators

Authors

  • Pierre Kuhn,

    Corresponding author
    1. Médecine et Réanimation néonatales, Service de Pédiatrie 2, Pôle Médico-chirurgical pédiatrique, Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France
    • Laboratoire d'Imagerie & Neurosciences Cognitives, UMR 7237 Université de Strasbourg/Centre National de la Recherche Scientifique, Strasbourg, France
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  • Claire Zores,

    1. Laboratoire d'Imagerie & Neurosciences Cognitives, UMR 7237 Université de Strasbourg/Centre National de la Recherche Scientifique, Strasbourg, France
    2. Médecine et Réanimation néonatales, Service de Pédiatrie 2, Pôle Médico-chirurgical pédiatrique, Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France
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  • Claire Langlet,

    1. Médecine et Réanimation néonatales, Service de Pédiatrie 2, Pôle Médico-chirurgical pédiatrique, Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France
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  • Benoît Escande,

    1. Médecine et Réanimation néonatales, Service de Pédiatrie 2, Pôle Médico-chirurgical pédiatrique, Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France
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  • Dominique Astruc,

    1. Médecine et Réanimation néonatales, Service de Pédiatrie 2, Pôle Médico-chirurgical pédiatrique, Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France
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  • André Dufour

    1. Laboratoire d'Imagerie & Neurosciences Cognitives, UMR 7237 Université de Strasbourg/Centre National de la Recherche Scientifique, Strasbourg, France
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Correspondence

Pierre Kuhn, Médecine et Réanimation néonatales, Service de Pédiatrie 2, Pôle médico-chirurgical pédiatrique Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Avenue Molière, 67098 Strasbourg, France.

Tel: +0033 388127786 |

Fax: +0033 388127132 |

Email: pierre.kuhn@chru-strasbourg.fr

and

Laboratoire de Neurosciences Cognitives et Adaptatives, Centre National de la Recherche Scientifique/Université de Strasbourg, 67000 Strasbourg, France.

Tel: +0033 388106759 |

Email: p.kuhn@unistra.fr

Abstract

Aim

To evaluate the impact of moderate noise on the sleep of very early preterm infants (VPI).

Methods

Observational study of 26 VPI of 26–31 weeks' gestation, with prospective measurements of sound pressure level and concomitant video records. Sound peaks were identified and classified according to their signal-to-noise ratio (SNR) above background noise. Prechtl's arousal states during sound peaks were assessed by two observers blinded to the purpose of the study. Changes in sleep/arousal states following sound peaks were compared with spontaneous changes during randomly selected periods without sound peaks.

Results

We identified 598 isolated sound peaks (5 ≤ SNR < 10 decibel slow response A (dBA), n = 518; 10 ≤ SNR < 15 dBA, n = 80) during sleep. Awakenings were observed during 33.8% (95% CI, 24–43.7%) of exposures to sound peaks of 5–10 dBA SNR and 39.7% (95% CI, 26–53.3%) of exposures to sound peaks of SNR 10–15 dBA, but only 11.7% (95% CI, 6.2–17.1%) of control periods. The proportions of awakenings following sound peaks were higher than the proportions of arousals during control periods (p < 0.005).

Conclusions

Moderate acoustic changes can disrupt the sleep of VPI, and efficient sound abatement measures are needed.

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