The first two authors contributed equally to this study.
Letters to the Editor
Letter: colorectal cancer screening
Article first published online: 17 DEC 2012
© 2012 Blackwell Publishing Ltd
Alimentary Pharmacology & Therapeutics
Volume 37, Issue 2, pages 284–285, January 2013
How to Cite
Lai, S.-W., Liao, K.-F. and Lai, H.-C. (2013), Letter: colorectal cancer screening. Alimentary Pharmacology & Therapeutics, 37: 284–285. doi: 10.1111/apt.12143
- Issue published online: 17 DEC 2012
- Article first published online: 17 DEC 2012
- Manuscript Accepted: 25 OCT 2012
- Manuscript Received: 20 OCT 2012
We read the meta-analysis by Hassan and colleagues with great interest. The authors reported that the detection rate of advanced neoplasia was higher with colonoscopy (relative risk = 3.56; 95% CI = 1.79–7.09) than that with faecal tests.
In our cross-sectional study in Taiwan, six subjects (0.14%) were found to have rectosigmoid adenocarcinomas among 4413 subjects undergoing flexible sigmoidoscopy during self-referred health examinations between 2001 and 2004. A population-based study using the Taiwan cancer registry database has shown that 25% of total colorectal cancers were located in the right side of the colon.
Therefore, flexible sigmoidoscopy cannot detect all colorectal cancers. Based on Hassan et al.'s and our findings, colonoscopy should be superior to sigmoidoscopy and faecal tests for detection of colorectal cancer in a screening setting.
Declaration of personal and funding interests: None.
- 2Association between rectosigmoid adenomas and cardiovascular risk factors: a hospital-based, cross-sectional study. Ann Acad Med Singapore 2009; 38: 630–6., , , , .