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British Journal of Clinical Pharmacology

Cover image for Vol. 47 Issue 4

April 1999

Volume 47, Issue 4

Pages 339–461

  1. Review

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      Therapeutic drug monitoring of immunosuppressant drugs (pages 339–350)

      Atholl Johnston and David W. Holt

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00911.x

  2. Drug delivery

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      Pharmacokinetics and bioavailability of oral 5′-deoxy-5-fluorouridine in cancer patients (pages 351–356)

      Van Der Heyden, Highley, De Bruijn, Tjaden, Reeuwijk, Van Slooten, Van Oosterom and Maes

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00899.x

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  3. Pharmacokinetics

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      Estimation of the initial distribution volume of glucose by an incremental plasma glucose level at 3 min after i.v. glucose in humans (pages 361–364)

      Kazuyoshi Hirota, Hironori Ishihara, Toshihito Tsubo and Akitomo Matsuki

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00889.x

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      A pharmacokinetic model for alpha interferon administered subcutaneously (pages 365–371)

      Etienne Chatelut, Lionel Rostaing, Nicolas Grégoire, Jean-Louis Payen, André Pujol, Jacques Izopet, Georges Houin and Pierre Canal

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00912.x

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      Pharmacokinetics and tolerability of oral rizatriptan in healthy male and female volunteers (pages 373–378)

      Lee, Conroy, Stepanavage, Mendel, Somers, McLoughlin, Olah, De Smet, Keymeulen and Rogers

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00917.x

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      Pharmacokinetic variability and strategy for therapeutic drug monitoring of saquinavir (SQV) in HIV-1 infected individuals (pages 379–382)

      Mario B. Regazzi, Paola Villani, Renato Maserati, Laura Cocchi, Roberto Giacchino, Daniela Burroni and Mauro Rettani

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00919.x

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  4. Drug disposition

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      Cellular uptake of fluvastatin, an inhibitor of HMG-CoA reductase, by rat cultured hepatocytes and human aortic endothelial cells (pages 383–389)

      Masakatsu Ohtawa, Naoki Masuda, Izumi Akasaka, Akinori Nakashima, Keiko Ochiai and Matsuko Moriyasu

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00901.x

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      Dietary caffeine as a probe agent for assessment of cytochrome P4501A2 activity in random urine samples (pages 397–402)

      Anna Nordmark, Stefan Lundgren, Sven Cnattingius and Anders Rane

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00918.x

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      Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4 (pages 403–412)

      David J. R. Foster, Andrew A. Somogyi and Felix Bochner

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00921.x

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  5. Pharmacokinetics and pharmacodynamics

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      Chronopharmacology of intravenous and oral modified release verapamil (pages 413–419)

      Karin Dilger, Klaus Eckhardt, Ute Hofmann, Klaus Kucher, Gerd Mikus and Michel Eichelbaum

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00910.x

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  6. Pharmacodynamics

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      Midazolam effects on prepulse inhibition of the acoustic blink reflex (pages 421–426)

      Hartmut Schächinger, Beatrice U. Müller, Werner Strobel, Wolf Langewitz and Rudolf Ritz

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00896.x

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      Impaired β-adrenoceptor mediated venodilation in patients with diabetes mellitus (pages 427–431)

      Kazuhiro Harada, Masami Ohmori, Yasuhiko Kitoh, Koh-ichi Sugimoto and Akio Fujimura

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00915.x

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      Effect of troglitazone on plasma lipid metabolism and lipoprotein lipase (pages 433–439)

      Junji Kobayashi, Izumi Nagashima, Minoru Hikita, Hideaki Bujo, Kazuo Takahashi, Masako Otabe, Nobuhiro Morisaki and Yasushi Saito

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00920.x

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  7. Drug interaction

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      A placebo-controlled study of interaction between nabumetone and acenocoumarol (pages 441–444)

      Pardo, García-Losa, Fernández-Pavón, Del Castillo, Pascual-García, García-Méndez and Dal-Ré

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00916.x

  8. Short reports

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      Functional significance of a C[RIGHTWARDS ARROW]A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine (pages 445–449)

      Christoph Sachse, Jürgen Brockmöller, Steffen Bauer and Ivar Roots

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00898.x

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      Effect of the CYP2D6*10 genotype on venlafaxine pharmacokinetics in healthy adult volunteers (pages 450–453)

      Tsuyoshi Fukuda, Isamu Yamamoto, Yuko Nishida, Qian Zhou, Masako Ohno, Kanji Takada and Junichi Azuma

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00913.x

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      Ticlopidine decreases the in vivo activity of CYP2C19 as measured by omeprazole metabolism (pages 454–457)

      Tomonori Tateishi, Toshio Kumai, Minoru Watanabe, Hironori Nakura, Masami Tanaka and Shinichi Kobayashi

      Version of Record online: 24 DEC 2001 | DOI: 10.1046/j.1365-2125.1999.00914.x

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  9. Letters to the Editors

    1. Top of page
    2. Review
    3. Drug delivery
    4. Pharmacokinetics
    5. Drug disposition
    6. Pharmacokinetics and pharmacodynamics
    7. Pharmacodynamics
    8. Drug interaction
    9. Short reports
    10. Letters to the Editors
    1. You have free access to this content
      (S)-ketoprofen accumulation in premature neonates with renal failure who were exposed to the racemate during pregnancy (pages 459–460)

      B. Bannwarth, F. Lagrange, F. Péhourcq, B. Llanas and J. L. Demarquez

      Version of Record online: 24 DEC 2001 | DOI: 10.1111/bcp.1999.47.4.459

    2. You have free access to this content
      Serum concentrations and clinical effects of risperidone in schizophrenic patients in Singapore—a preliminary report (pages 460–461)

      How Sung Lee, Chay Hoon Tan, Yok Moi Khoo, Kuan Tsee Chee, Kim Eng Wong, Siow Ann Chong, Rathi Mahendran, Hwa Ling Yap, Bee Lee Low, Chih Huei Choo and Angelina Chan

      Version of Record online: 24 DEC 2001 | DOI: 10.1111/bcp.1999.47.4.460

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