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British Journal of Clinical Pharmacology

Cover image for Vol. 68 Issue 5

November 2009

Volume 68, Issue 5

Pages 647–799

  1. Editors' view

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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  2. New drug mechanisms

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Maraviroc and raltegravir (pages 651–652)

      Eline A. Dubois and Adam F. Cohen

      Article first published online: 21 JUL 2009 | DOI: 10.1111/j.1365-2125.2009.03503.x

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      Aliskiren (pages 653–654)

      Eline A. Dubois and Adam F. Cohen

      Article first published online: 21 JUL 2009 | DOI: 10.1111/j.1365-2125.2009.03504.x

  3. Review article

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Effect of topiramate on acid–base balance: extent, mechanism and effects (pages 655–661)

      Nasir Mirza, Anthony G. Marson and Munir Pirmohamed

      Article first published online: 7 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03521.x

  4. Clinical trials

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      The effect of allopurinol on the cerebral vasculature of patients with subcortical stroke; a randomized trial (pages 662–668)

      Jesse Dawson, Terrence J. Quinn, Craig Harrow, Kennedy R. Lees and Matthew R. Walters

      Article first published online: 21 JUL 2009 | DOI: 10.1111/j.1365-2125.2009.03497.x

  5. Pharmacokinetics

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Population pharmacokinetic analysis of varenicline in adult smokers (pages 669–681)

      Patanjali Ravva, Marc R. Gastonguay, Thomas G. Tensfeldt and Hélène M. Faessel

      Article first published online: 7 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03520.x

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      Influence of CYP2C19 polymorphism on the pharmacokinetics of nelfinavir and its active metabolite (pages 682–689)

      Bharat D. Damle, Howard Uderman, Pinaki Biswas, Penelope Crownover, Chang Lin and Paul Glue

      Article first published online: 21 JUL 2009 | DOI: 10.1111/j.1365-2125.2009.03499.x

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      A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans (pages 690–699)

      Jackson K. Mukonzo, Daniel Röshammar, Paul Waako, Maria Andersson, Takashi Fukasawa, Lili Milani, Jan Olof Svensson, Jasper Ogwal-Okeng, Lars L. Gustafsson and Eleni Aklillu

      Article first published online: 7 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03516.x

  6. Pharmacokinetic dynamic relationships

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Modelling the occurrence and severity of enoxaparin-induced bleeding and bruising events (pages 700–711)

      Michael A. Barras, Stephen B. Duffull, John J. Atherton and Bruce Green

      Article first published online: 7 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03518.x

  7. Drug interactions

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Inhibition of the active principle of the weak opioid tilidine by the triazole antifungal voriconazole (pages 712–720)

      Barbara Grün, Stefanie Krautter, Klaus-Dieter Riedel and Gerd Mikus

      Article first published online: 21 JUL 2009 | DOI: 10.1111/j.1365-2125.2009.03498.x

  8. Pharmacogenetics

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion (pages 721–730)

      Xi He, Leah M. Hesse, Suwagmani Hazarika, Gina Masse, Jerold S. Harmatz, David J. Greenblatt and Michael H. Court

      Article first published online: 7 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03519.x

  9. Drug safety

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Inhaled tiotropium bromide and risk of stroke (pages 731–736)

      Anthony Grosso, Ian Douglas, Aroon D. Hingorani, Raymond MacAllister, Richard Hubbard and Liam Smeeth

      Article first published online: 7 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03517.x

  10. Drugs in pregnancy and lactation

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Albendazole and its metabolites in the breast milk of lactating women following a single oral dose of albendazole (pages 737–742)

      Ahmed M. Abdel-tawab, Mark Bradley, Essam A. Ghazaly, John Horton and Maged El-Setouhy

      Article first published online: 10 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03524.x

  11. Pharmacoepidemiology

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Sudden death in patients receiving drugs tending to prolong the QT interval (pages 743–751)

      Kate Jolly, Michael D. Gammage, Kar Keung Cheng, Peter Bradburn, Miriam V. Banting and Michael J. S. Langman

      Article first published online: 21 JUL 2009 | DOI: 10.1111/j.1365-2125.2009.03496.x

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      Population impact of regulatory activity restricting prescribing of COX-2 inhibitors: ecological study (pages 752–764)

      Benedict W. Wheeler, Chris Metcalfe, David Gunnell, Peter Stephens and Richard M. Martin

      Article first published online: 21 JUL 2009 | DOI: 10.1111/j.1365-2125.2009.03500.x

  12. Short report

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
    1. You have free access to this content
      Enzyme therapy in Fabry disease: severe adverse events associated with anti-agalsidase cross-reactive IgG antibodies (pages 765–769)

      Chloe Tesmoingt, Olivier Lidove, Axele Reberga, Marguerite Thetis, Chloe Ackaert, Pascale Nicaise, Philippe Arnaud and Thomas Papo

      Article first published online: 21 JUL 2009 | DOI: 10.1111/j.1365-2125.2009.03501.x

  13. Letters to the editors

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
    1. You have free access to this content
      Characterization of a novel TPMT mutation associated with azathioprine-induced myelosuppression (pages 770–772)

      Tiphaine Adam De Beaumais, May Fakhoury, Benedicte Pigneur, Sheila Viola, Yves Medard, Franck Broly and Evelyne Jacqz-Aigrain

      Article first published online: 5 MAY 2009 | DOI: 10.1111/j.1365-2125.2009.03439.x

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      Reply to Frank Wells' letter (page 778)

      James M. Ritter

      Article first published online: 4 SEP 2009 | DOI: 10.1111/j.1365-2125.2009.03539.x

  14. Book review

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      Frontiers of Neurology and Neuroscience (page 779)

      ELEMER SZABADI

      Article first published online: 7 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03515.x

  15. Obituary

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
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      John Feely : MD, MA, BSC, FRCPE, FRCPI, FFPHMI (Hon) (pages 780–781)

      Phil Routledge and David Williams

      Article first published online: 5 AUG 2009 | DOI: 10.1111/j.1365-2125.2009.03514.x

  16. Abstracts

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
    1. You have free access to this content
  17. Mandarin translations section

    1. Top of page
    2. Editors' view
    3. New drug mechanisms
    4. Review article
    5. Clinical trials
    6. Pharmacokinetics
    7. Pharmacokinetic dynamic relationships
    8. Drug interactions
    9. Pharmacogenetics
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Pharmacoepidemiology
    13. Short report
    14. Letters to the editors
    15. Book review
    16. Obituary
    17. Abstracts
    18. Mandarin translations section
    1. You have free access to this content
      Translation Section (pages 794–799)

      Article first published online: 6 NOV 2009 | DOI: 10.1111/j.1365-2125.2009.03554.x

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