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British Journal of Clinical Pharmacology

Cover image for Vol. 74 Issue 5

November 2012

Volume 74, Issue 5

Pages 731–902

  1. Editorial commentary

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
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      Fifty years after thalidomide; what role for drug regulators? (pages 731–733)

      Hans-Georg Eichler, Eric Abadie, Mary Baker and Guido Rasi

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04255.x

  2. Commentaries

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
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      Perspective on dabigatran etexilate dosing: why not follow standard pharmacological principles? (pages 734–740)

      Paul K. L. Chin, Jane W. A. Vella-Brincat, Murray L. Barclay and Evan J. Begg

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04266.x

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  3. Reviews

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
    2. You have free access to this content
      Symmetrical analysis of risk–benefit (pages 757–761)

      John B. Warren, Simon Day and Peter Feldschreiber

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04265.x

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      Geriatric pharmacology and pharmacotherapy education for health professionals and students: a systematic review (pages 762–773)

      Carolina J. P. W. Keijsers, Larissa van Hensbergen, Lotte Jacobs, Jacobus R. B. J. Brouwers, Dick J. de Wildt, Olle Th. J. ten Cate and Paul A. F. Jansen

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04268.x

  4. Pharmacokinetics

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
      Trends in oral drug bioavailability following bariatric surgery: examining the variable extent of impact on exposure of different drug classes (pages 774–787)

      Adam S. Darwich, Kathryn Henderson, Angela Burgin, Nicola Ward, Janet Whittam, Basil J. Ammori, Darren M. Ashcroft and Amin Rostami-Hodjegan

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04284.x

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      Single and multiple dose intravenous and oral pharmacokinetics of the hedgehog pathway inhibitor vismodegib in healthy female subjects (pages 788–796)

      Richard A. Graham, Cornelis E. C. A. Hop, Marie T. Borin, Bert L. Lum, Dawn Colburn, Ilsung Chang, Young G. Shin, Vikram Malhi, Jennifer A. Low and Mark J. Dresser

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04281.x

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      Influence of adult age on the total and free clearance and protein binding of (R)- and (S)-warfarin (pages 797–805)

      Berit Packert Jensen, Paul Ken Leong Chin, Rebecca Lee Roberts and Evan James Begg

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04259.x

  5. Pharmacokinetic dynamic relationships

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
      Bioactivity of enoxaparin in critically ill patients with normal renal function (pages 806–814)

      Ghazaleh Gouya, Stefan Palkovits, Stylianos Kapiotis, Christian Madl, Gottfried Locker, Alexander Stella, Michael Wolzt and Gottfried Heinz

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04285.x

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      Population PK/PD analysis of metformin using the signal transduction model (pages 815–823)

      Jung-woo Chae, In-hwan Baek, Byung-yo Lee, Seong-kwon Cho and Kwang-il Kwon

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04260.x

  6. Drug interactions

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
    2. You have free access to this content
      Inhibition of CYP2D6-mediated tramadol O-demethylation in methadone but not buprenorphine maintenance patients (pages 835–841)

      Janet K. Coller, Jennifer R. Michalakas, Heather M. James, Aaron L. Farquharson, Joel Colvill, Jason M. White and Andrew A. Somogyi

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04256.x

  7. Pharmacogenetics

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
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      Development and validation of a PCR-based assay for the selection of patients more likely to benefit from therapeutic treatment with alkylating drugs (pages 842–853)

      Dimitra T. Stefanou, Hara Episkopou, Soterios A. Kyrtopoulos, Aristotelis Bamias, Maria Gkotzamanidou, Christina Bamia, Christina Liakou, Margarita Bekyrou, Petros P. Sfikakis, Meletios-Athanasios Dimopoulos and Vassilis L. Souliotis

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04274.x

  8. Drug metabolism

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
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      Contribution of CYP2C19 and CYP3A4 to the formation of the active nortilidine from the prodrug tilidine (pages 854–863)

      Barbara Grün, Ulrike Merkel, Klaus-Dieter Riedel, Johanna Weiss and Gerd Mikus

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04261.x

  9. Paediatric clinical pharmacology

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
      Population pharmacokinetic model of canrenone after intravenous administration of potassium canrenoate to paediatric patients (pages 864–872)

      Maysa Suyagh, Ahmed F. Hawwa, Paul S. Collier, Jeffrey S. Millership, Prashant Kole, Muriel Millar, Mike D. Shields, Henry L. Halliday and James C. McElnay

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04257.x

  10. Drugs in pregnancy and lactation

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
  11. Short report

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
      Safety profile of enantiomers vs. racemic mixtures: it's the same? (pages 886–889)

      Céline Caillet, Laurence Chauvelot-Moachon, Jean-Louis Montastruc, Haleh Bagheri and French Association of Regional Pharmacovigilance Centers

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04262.x

  12. Letter to the editors

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
      Suicide attempt with an overdose of imatinib (pages 890–892)

      Osamu Iketani, Tomoki Ueda, Yasuko Yamayoshi, Masaya Yamaguchi, Shunichi Kawamura and Shinichiro Okamoto

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04275.x

  13. Book review

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
  14. Mandarin translations section

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
  15. Erratum

    1. Top of page
    2. Editorial commentary
    3. Commentaries
    4. Reviews
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Drug interactions
    8. Pharmacogenetics
    9. Drug metabolism
    10. Paediatric clinical pharmacology
    11. Drugs in pregnancy and lactation
    12. Short report
    13. Letter to the editors
    14. Book review
    15. Mandarin translations section
    16. Erratum
    1. You have free access to this content
      Erratum (page 902)

      Version of Record online: 9 OCT 2012 | DOI: 10.1111/j.1365-2125.2012.04463.x

      This article corrects:

      Abstracts of the Dutch Society of Clinical Pharmacology and Biopharmacy Meeting of October 4, 2010

      Vol. 72, Issue 5, 843–863, Version of Record online: 11 OCT 2011

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