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British Journal of Clinical Pharmacology

Cover image for Vol. 75 Issue 4

April 2013

Volume 75, Issue 4

Pages i–ii, 885–1173

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Issue Information (pages i–ii)

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04431.x

  2. Stem cells: pharmacology and therapeutics

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Stem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet? (pages 885–896)

      Richard Kia, Rowena L. C. Sison, James Heslop, Neil R. Kitteringham, Neil Hanley, John S. Mills, B. Kevin Park and Chris E. P. Goldring

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04360.x

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      Stem cell-derived endothelial cells for cardiovascular disease: a therapeutic perspective (pages 897–906)

      Daniel M. Reed, Gabor Foldes, Sian E. Harding and Jane A. Mitchell

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04361.x

    3. You have full text access to this OnlineOpen article
  3. Reviews

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
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      Incidence and risk of hypertension with vandetanib in cancer patients: a systematic review and meta-analysis of clinical trials (pages 919–930)

      Wei-Xiang Qi, Zan Shen, Feng Lin, Yuan-jue Sun, Da-liu Min, Li-Na Tang, Ai-Na He and Yang Yao

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04417.x

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      Current and emerging antiviral treatments for hepatitis C infection (pages 931–943)

      Joseph S. Doyle, Esther Aspinall, Danny Liew, Alexander J. Thompson and Margaret E. Hellard

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04419.x

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      Overview of pharmacoeconomic modelling methods (pages 944–950)

      Zanfina Ademi, Hansoo Kim, Ella Zomer, Christopher M. Reid, Bruce Hollingsworth and Danny Liew

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04421.x

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      The Hypertension in the Very Elderly Trial – latest data (pages 951–954)

      Omar Mukhtar and Stephen H. D. Jackson

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04427.x

  4. Commentaries

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Incident diabetes and statins: the blemish of an undisputed heavy weight champion? (pages 955–958)

      Eiman Jahangir, Sergio Fazio and Uchechukwu K. A. Sampson

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04445.x

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  5. Clinical trials

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
    2. You have full text access to this OnlineOpen article
      Exenatide at therapeutic and supratherapeutic concentrations does not prolong the QTc interval in healthy subjects (pages 979–989)

      Börje Darpö, Sager Philip, Leigh MacConell, Brenda Cirincione, Malcolm Mitchell, Jenny Han, Wenying Huang, Jaret Malloy, Christine Schulteis, Larry Shen and Lisa Porter

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04416.x

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      A phase 1 study to evaluate the effect of dolutegravir on renal function via measurement of iohexol and para-aminohippurate clearance in healthy subjects (pages 990–996)

      Justin Koteff, Julie Borland, Shuguang Chen, Ivy Song, Amanda Peppercorn, Takaaki Koshiba, Courtney Cannon, Heather Muster and Stephen C. Piscitelli

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04440.x

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      Neuropsychometric correlates of efavirenz pharmacokinetics and pharmacogenetics following a single oral dose (pages 997–1006)

      Daniel H. Johnson, Tebeb Gebretsadik, Ayumi Shintani, Gail Mayo, Edward P. Acosta, C. Michael Stein and David W. Haas

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04454.x

  6. Pharmacokinetics

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Prediction of free imatinib concentrations based on total plasma concentrations in patients with gastrointestinal stromal tumours (pages 1007–1018)

      Amina Haouala, Nicolas Widmer, Monia Guidi, Michael Montemurro, Serge Leyvraz, Thierry Buclin, Chin B. Eap, Laurent A. Decosterd and Chantal Csajka

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04422.x

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      Predicted metabolic drug clearance with increasing adult age (pages 1019–1028)

      Thomas M. Polasek, Farhaan Patel, Berit P. Jensen, Michael J. Sorich, Michael D. Wiese and Matthew P. Doogue

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04446.x

  7. Pharmacokinetic dynamic relationships

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
  8. Drug interactions

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers (pages 1041–1052)

      Michael J. Hanley, Gina Masse, Jerold S. Harmatz, Paul F. Cancalon, Gregory G. Dolnikowski, Michael H. Court and David J. Greenblatt

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04450.x

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  9. Therapeutics

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Tramadol and hypoglycaemia: comparison with other step 2 analgesic drugs (pages 1063–1067)

      Cindy Bourne, Aurore Gouraud, Amélie Daveluy, Aurélie Grandvuillemin, Pascal Auriche, Jacques Descotes, Thierry Vial and French Association of Regional Pharmacovigilance Centres

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04451.x

  10. Paediatric clinical pharmacology

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      External evaluation of population pharmacokinetic models of vancomycin in neonates: the transferability of published models to different clinical settings (pages 1068–1080)

      Wei Zhao, Florentia Kaguelidou, Valérie Biran, Daolun Zhang, Karel Allegaert, Edmund V. Capparelli, Nick Holford, Toshimi Kimura, Yoke-Lin Lo, José-Esteban Peris, Alison Thomson, John N. van den Anker, May Fakhoury and Evelyne Jacqz-Aigrain

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04406.x

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      Pharmacokinetic comparison of inhaled fixed combination vs. the free combination of beclomethasone and formoterol pMDIs in asthmatic children (pages 1081–1088)

      Bo L. K. Chawes, Annalisa Piccinno, Eskil Kreiner-Møller, Nadja H. Vissing, Porntiva Poorisrisak, Li Mortensen, Erik Nilson, Amalie Bisgaard, Anna Dossing, Maja Deleuran, Nanna L. Skytt, Nasim Samandari, Francesco Sergio, Giorgia Ciurlia, Gianluigi Poli, Daniela Acerbi and Hans Bisgaard

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04459.x

  11. Methods in clinical pharmacology

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Reasons that prevent the inclusion of Alzheimer's disease patients in clinical trials (pages 1089–1097)

      Adeline Rollin-Sillaire, Laetitia Breuilh, Julia Salleron, Stéphanie Bombois, Pascaline Cassagnaud, Vincent Deramecourt, Marie-Anne Mackowiak and Florence Pasquier

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04423.x

  12. Drug safety

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Observational study on safety and tolerability of duloxetine in the treatment of female stress urinary incontinence in German routine practice (pages 1098–1108)

      Martin C. Michel, Anette Minarzyk, Inka Schwerdtner, Deborah Quail, Hans D. Methfessel and Hans-Joachim Weber

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04389.x

    2. You have free access to this content
      What can we learn from parents about enhancing participation in pharmacovigilance? (pages 1109–1117)

      Janine Arnott, Hannah Hesselgreaves, Anthony J. Nunn, Matthew Peak, Munir Pirmohamed, Rosalind L. Smyth, Mark A. Turner and Bridget Young

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04441.x

  13. Pharmacoepidemiology

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Statins and risk of treated incident diabetes in a primary care population (pages 1118–1124)

      Nur Lisa Zaharan, David Williams and Kathleen Bennett

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04403.x

      Corrected by:

      Corrigendum: Corrigendum

      Vol. 78, Issue 3, 677–679, Article first published online: 21 AUG 2014

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      Psychotropic drugs and risk of motor vehicle accidents: a population-based case-control study (pages 1125–1133)

      Chia-Ming Chang, Erin Chia-Hsuan Wu, Chuan-Yu Chen, Kuan-Yi Wu, Hsin-Yi Liang, Yeuk-Lun Chau, Chi-Shin Wu, Keh-Ming Lin and Hui-Ju Tsai

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04410.x

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      Effects of preconceptional paternal drug exposure on birth outcomes: cohort study of 340 000 pregnancies using Norwegian population-based databases (pages 1134–1141)

      Anders Engeland, Tone Bjørge, Anne Kjersti Daltveit, Svetlana Skurtveit, Siri Vangen, Stein Emil Vollset and Kari Furu

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04426.x

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  14. Letters to the editors

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
    2. You have free access to this content
      Epigenetic drugs for Alzheimer's disease (pages 1152–1153)

      Jacob Peedicayil

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04444.x

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      Epigenetic drugs for Alzheimer's disease: hopes and challenges (pages 1154–1155)

      Filippo Caraci, Gian Marco Leggio, Filippo Drago and Salvatore Salomone

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04443.x

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      A case of acute liver failure due to etodolac (pages 1156–1157)

      Fotios Sampaziotis, Rebecca J. Brais and William J. H. Griffiths

      Article first published online: 15 MAR 2013 | DOI: 10.1111/j.1365-2125.2012.04448.x

  15. Book review

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
  16. Mandarin translations section

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
  17. Erratum

    1. Top of page
    2. Issue Information
    3. Stem cells: pharmacology and therapeutics
    4. Reviews
    5. Commentaries
    6. Clinical trials
    7. Pharmacokinetics
    8. Pharmacokinetic dynamic relationships
    9. Drug interactions
    10. Therapeutics
    11. Paediatric clinical pharmacology
    12. Methods in clinical pharmacology
    13. Drug safety
    14. Pharmacoepidemiology
    15. Letters to the editors
    16. Book review
    17. Mandarin translations section
    18. Erratum
    1. You have free access to this content
      Erratum (page 1171)

      Article first published online: 15 MAR 2013 | DOI: 10.1111/bcp.12107

      This article corrects:

      Applications of stable isotopes in clinical pharmacology

      Vol. 72, Issue 6, 879–897, Article first published online: 9 NOV 2011

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    3. You have free access to this content

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