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British Journal of Clinical Pharmacology

Cover image for Vol. 75 Issue 5

May 2013

Volume 75, Issue 5

Pages i–ii, 1175–1379

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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      Issue Information (pages i–ii)

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04432.x

  2. Reviews

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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    2. You have free access to this content
    3. You have free access to this content
  3. Appreciation

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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      Sir David Jack: an extraordinary drug discoverer and developer (pages 1213–1218)

      Clive Page and Patrick Humphrey

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04467.x

  4. Commentary

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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  5. Translational research

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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      Half-life prolongation of therapeutic proteins by conjugation to ATIII-binding pentasaccharides: a first-in-human study of CarboCarrier® insulin (pages 1221–1230)

      André M. M. Miltenburg, Marita Prohn, Jacqueline H. M. van Kuijk, Renger G. Tiessen, Martin de Kort and Rob J. W. Berg

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04460.x

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      A randomized phase I study of methanesulfonyl fluoride, an irreversible cholinesterase inhibitor, for the treatment of Alzheimer's disease (pages 1231–1239)

      Donald E. Moss, Ruggero G. Fariello, Jörg Sahlmann, Isabel Sumaya, Federica Pericle and Enrico Braglia

      Version of Record online: 8 APR 2013 | DOI: 10.1111/bcp.12018

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  6. Pharmacodynamics

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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      Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics – results from single oral dose studies in healthy volunteers (pages 1240–1254)

      S. Aubrey Stoch, Stefan Zajic, Julie A. Stone, Deborah L. Miller, Lucas van Bortel, Kenneth C. Lasseter, Barnali Pramanik, Caroline Cilissen, Qi Liu, Lida Liu, Boyd B. Scott, Deborah Panebianco, Yu Ding, Keith Gottesdiener and John A. Wagner

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04471.x

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      Bioequipotency of idraparinux and idrabiotaparinux after once weekly dosing in healthy volunteers and patients treated for acute deep vein thrombosis (pages 1255–1264)

      Marc Trellu, Jean-Baptiste Fau, Pierre Cortez, Sue Cheng, Isabelle Paty, Emmanuelle Boëlle, François Donat and Ger-Jan Sanderink

      Version of Record online: 8 APR 2013 | DOI: 10.1111/bcp.12009

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  7. Pharmacokinetics

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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      Prophylactic ranitidine treatment in critically ill children – a population pharmacokinetic study (pages 1265–1276)

      Ahmed F. Hawwa, Paul M. Westwood, Paul S. Collier, Jeffrey S. Millership, Shirish Yakkundi, Gillian Thurley, Mike D. Shields, Anthony J. Nunn, Henry L. Halliday and James C. McElnay

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04473.x

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      Statistical tools for dose individualization of mycophenolic acid and tacrolimus co-administered during the first month after renal transplantation (pages 1277–1288)

      Flora T. Musuamba, Michel Mourad, Vincent Haufroid, Martine De Meyer, Arnaud Capron, Isabelle K. Delattre, Roger K. Verbeeck and Pierre Wallemacq

      Version of Record online: 8 APR 2013 | DOI: 10.1111/bcp.12007

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      Safety, tolerability and pharmacokinetics of a human anti-interleukin-13 monoclonal antibody (CNTO 5825) in an ascending single-dose first-in-human study (pages 1289–1298)

      Bart van Hartingsveldt, Ivo P. Nnane, Esther Bouman-Thio, Matthew J. Loza, Alexa Piantone, Hugh M. Davis and Kevin J. Petty

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04477.x

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      Safety, tolerability and pharmacokinetics of the histamine H3 receptor antagonist, ABT-288, in healthy young adults and elderly volunteers (pages 1299–1311)

      Ahmed A. Othman, George Haig, Hana Florian, Charles Locke, Jun Zhang and Sandeep Dutta

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04472.x

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  8. Pharmacokinetic dynamic relationships

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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      Vitamin D3 supplementation scheme in HIV-infected patients based upon pharmacokinetic modelling of 25-hydroxycholecalciferol (pages 1312–1320)

      Frantz Foissac, Jean-Marc Tréluyer, Jean-Claude Souberbielle, Hafeda Rostane, Saïk Urien and Jean-Paul Viard

      Version of Record online: 8 APR 2013 | DOI: 10.1111/bcp.12006

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  9. Drug interactions

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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      Pharmacokinetics of 450 mg ropivacaine with and without epinephrine for combined femoral and sciatic nerve block in lower extremity surgery. A pilot study (pages 1321–1327)

      Karin P. W. Schoenmakers, Tom B. Vree, Nigel T. M. Jack, Bart van den Bemt, Jacques van Limbeek and Rudolf Stienstra

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04470.x

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      Pharmacokinetics and central nervous system effects of the novel dual NK1/NK3 receptor antagonist GSK1144814 in alcohol-intoxicated volunteers (pages 1328–1339)

      Erik T. te Beek, Justin L. Hay, Jonathan N. Bullman, Clare Burgess, Kimberly J. Nahon, Erica S. Klaassen, Frank A. Gray and Joop M. A. van Gerven

      Version of Record online: 8 APR 2013 | DOI: 10.1111/bcp.12004

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  10. Pharmacogenetics

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
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      Analgesia and central side-effects: two separate dimensions of morphine response (pages 1340–1350)

      Joanne M. Droney, Sophy K. Gretton, Hiroe Sato, Joy R. Ross, Ruth Branford, Kenneth I. Welsh, William Cookson and Julia Riley

      Version of Record online: 8 APR 2013 | DOI: 10.1111/bcp.12008

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  11. Drug safety

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
    1. You have free access to this content
      Dronedarone-associated acute renal failure: evidence coming from the Italian spontaneous ADR reporting database (pages 1351–1355)

      Chiara Biagi, Mauro Venegoni, Mauro Melis, Elena Buccellato, Nicola Montanaro and Domenico Motola

      Version of Record online: 8 APR 2013 | DOI: 10.1111/bcp.12005

  12. Pharmacoepidemiology

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
    1. You have free access to this content
  13. Letters to the editors

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
    1. You have full text access to this OnlineOpen article
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      Response to the comments from Drs Shimazawa and Ikeda (pages 1368–1369)

      Rashmi R. Shah and Devron R. Shah

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04461.x

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      Antidepressant use and gestational hypertension: does evidence support causality? (pages 1373–1374)

      Luke E. Grzeskowiak, Lars H. Pedersen and Janna L. Morrison

      Version of Record online: 8 APR 2013 | DOI: 10.1111/j.1365-2125.2012.04468.x

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  14. Book review

    1. Top of page
    2. Issue Information
    3. Reviews
    4. Appreciation
    5. Commentary
    6. Translational research
    7. Pharmacodynamics
    8. Pharmacokinetics
    9. Pharmacokinetic dynamic relationships
    10. Drug interactions
    11. Pharmacogenetics
    12. Drug safety
    13. Pharmacoepidemiology
    14. Letters to the editors
    15. Book review
    1. You have free access to this content

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