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British Journal of Clinical Pharmacology

Cover image for British Journal of Clinical Pharmacology

December 2013

Volume 76, Issue 6

Pages i–iii, 841–1001

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
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      Issue Information (pages i–iii)

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/j.1365-2125.2012.04439.x

  2. Commentary

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
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      Clinical Pharmacology Knowledge, Opportunities and Working Strengths (CPKNOWS): a competency model for pursuit of excellence in clinical pharmacology (pages 841–845)

      Keith A. Nieforth, Hisham Y. Abdallah, Patrick Smith, Michael Derks, Bruno Boutouyrie, Nenad Sarapa and Richard W. Peck

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12119

  3. Clinical Trials

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
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      Peripheral selectivity of the novel cannabinoid receptor antagonist TM38837 in healthy subjects (pages 846–857)

      Linda E. Klumpers, Marianne Fridberg, Marieke L. de Kam, Paul B. Little, Niels Ole Jensen, Hendrik D. Kleinloog, Christian E. Elling and Joop M. A. van Gerven

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12141

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      Pharmacokinetic interactions and safety evaluations of coadministered tafenoquine and chloroquine in healthy subjects (pages 858–867)

      Ann K. Miller, Emma Harrell, Li Ye, Sharon Baptiste-Brown, Jőrg-Peter Kleim, Colin Ohrt, Stephan Duparc, Jörg J. Möhrle, Alison Webster, Sandra Stinnett, Arlene Hughes, Sandy Griffith and Andrew P. Beelen

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12160

  4. Pharmacokinetics

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
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      An exploratory microdialysis study investigating the effect of repeated application of a diclofenac epolamine medicated plaster on prostaglandin concentrations in skeletal muscle after standardized physical exercise (pages 880–887)

      Angela Burian, Valeria Frangione, Stefano Rovati, Giuseppe Mautone, Chiara Leuratti, Angelo Vaccani, Richard Crevenna, Mohammad Keilani, Bernhard Burian, Martin Brunner and Markus Zeitlinger

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12125

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      Pharmacokinetics and pharmacodynamics of ponesimod, a selective S1P1 receptor modulator, in the first-in-human study (pages 888–896)

      Patrick Brossard, Hartmut Derendorf, Jian Xu, Haidar Maatouk, Atef Halabi and Jasper Dingemanse

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12129

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      Population pharmacokinetics of recombinant human C1 inhibitor in patients with hereditary angioedema (pages 897–907)

      Colm Farrell, Siobhan Hayes, Anurag Relan, Edwin S. van Amersfoort, Rienk Pijpstra and C. Erik Hack

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12132

  5. Pharmacokinetic dynamic relationships

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
    1. You have full text access to this OnlineOpen article
      Effect of extremes of body weight on the pharmacokinetics, pharmacodynamics, safety and tolerability of apixaban in healthy subjects (pages 908–916)

      Vijay V. Upreti, Jessie Wang, Yu Chen Barrett, Wonkyung Byon, Rebecca A. Boyd, Janice Pursley, Frank P. LaCreta and Charles E. Frost

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12114

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      Pharmacokinetic–pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects (pages 917–931)

      D. Hamish Wright, Julie A. Stone, Tami M. Crumley, Larissa Wenning, Wei Zheng, Kerri Yan, Amy Yifan Yang, Li Sun, Caroline Cilissen, Steven Ramael, Anne Hermanowski-Vosatka, Ronald B. Langdon, Keith M. Gottesdiener, John A. Wagner and Eseng Lai

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12131

  6. Therapeutics

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
    1. You have free access to this content
      Understanding the dose–response relationship of allopurinol: predicting the optimal dosage (pages 932–938)

      Garry G. Graham, Diluk R. W. Kannangara, Sophie L. Stocker, Ian Portek, Kevin D. Pile, Praveen L. Indraratna, Indira Datta, Kenneth M. Williams and Richard O. Day

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12126

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      The combined use of disease activity and infliximab serum trough concentrations for early prediction of (non-)response to infliximab in rheumatoid arthritis (pages 939–945)

      Bart J. F. van den Bemt, Alfons A. den Broeder, Gert-Jan Wolbink, Aatke van den Maas, Yechiel A. Hekster, Piet L. C. M. van Riel, H. Bart Benraad and Frank H. J. van den Hoogen

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12142

  7. Human Toxicology

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
    1. You have free access to this content
  8. Methods in Clinical Pharmacology

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
    1. You have free access to this content
      A novel approach to pharmaco-EEG for investigating analgesics: assessment of spectral indices in single-sweep evoked brain potentials (pages 951–963)

      Mikkel Gram, Carina Graversen, Anders K. Nielsen, Thomas Arendt-Nielsen, Carsten D. Mørch, Trine Andresen and Asbjørn M. Drewes

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12120

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      Not-in-trial simulation I: Bridging cardiovascular risk from clinical trials to real-life conditions (pages 964–972)

      Anne S. Y. Chain, Jeanne P. Dieleman, Charlotte van Noord, Albert Hofman, Bruno H. Ch. Stricker, Meindert Danhof, Miriam C. J. M. Sturkenboom and Oscar Della Pasqua

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12151

  9. Drug safety

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
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      Effects of MHRA drug safety advice on time trends in prescribing volume and indices of clinical toxicity for quinine (pages 973–979)

      Paul Acheampong, Gill Cooper, Behshad Khazaeli, David J. Lupton, Sue White, Margaret T. May and Simon H. L. Thomas

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12130

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      Junior doctors' perceptions of their self-efficacy in prescribing, their prescribing errors and the possible causes of errors (pages 980–987)

      Cristín Ryan, Sarah Ross, Peter Davey, Eilidh M. Duncan, Shona Fielding, Jill J. Francis, Marie Johnston, Jean Ker, Amanda Jane Lee, Mary Joan MacLeod, Simon Maxwell, Gerard McKay, James McLay, David J. Webb and Christine Bond

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12154

  10. Drugs in pregnancy and lactation

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
    1. You have free access to this content
      Tacrolimus placental transfer at delivery and neonatal exposure through breast milk (pages 988–996)

      Songmao Zheng, Thomas R. Easterling, Karen Hays, Jason G. Umans, Menachem Miodovnik, Shannon Clark, Justina C. Calamia, Kenneth E. Thummel, Danny D. Shen, Connie L. Davis and Mary F. Hebert

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12122

  11. Letters

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
    1. You have free access to this content
      Is the dose of dabigatran really more predictable than warfarin? (pages 997–998)

      Daniel F. B. Wright, Hesham S. Al-Sallami and Stephen B. Duffull

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/bcp.12144

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  12. Book review

    1. Top of page
    2. Issue Information
    3. Commentary
    4. Clinical Trials
    5. Pharmacokinetics
    6. Pharmacokinetic dynamic relationships
    7. Therapeutics
    8. Human Toxicology
    9. Methods in Clinical Pharmacology
    10. Drug safety
    11. Drugs in pregnancy and lactation
    12. Letters
    13. Book review
    1. You have free access to this content

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