British Journal of Clinical Pharmacology

Cover image for Vol. 82 Issue 3

September 2016

Volume 82, Issue 3

Pages 575–894

  1. ISSUE INFORMATION

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have free access to this content
      Issue Information (pages 575–577)

      Version of Record online: 8 AUG 2016 | DOI: 10.1111/bcp.12772

  2. ISSUE HIGHLIGHTS

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have free access to this content
      Issue Highlights (pages 578–579)

      Version of Record online: 8 AUG 2016 | DOI: 10.1111/bcp.13073

  3. EDITORIAL

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have free access to this content
  4. SYSTEMATIC REVIEWS

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have free access to this content
      The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta-analysis (pages 583–623)

      Amy T. Page, Rhonda M. Clifford, Kathleen Potter, Darren Schwartz and Christopher D. Etherton-Beer

      Version of Record online: 13 JUN 2016 | DOI: 10.1111/bcp.12975

      • image
      • image
      • image
      • image
      • image
      • image
    2. Use of antipsychotics and risk of myocardial infarction: a systematic review and meta-analysis (pages 624–632)

      Zheng-he Yu, Hai-yin Jiang, Li Shao, Yuan-yue Zhou, Hai-yan Shi and Bing Ruan

      Version of Record online: 23 MAY 2016 | DOI: 10.1111/bcp.12985

      • image
      • image
      • image
    3. Direct oral anticoagulants for stroke prevention in patients with atrial fibrillation: meta-analysis by geographic region with a focus on European patients (pages 633–644)

      Antonio Gómez-Outes, Ana-Isabel Terleira-Fernández, Gonzalo Calvo-Rojas, M. Luisa Suárez-Gea and Emilio Vargas-Castrillón

      Version of Record online: 17 JUN 2016 | DOI: 10.1111/bcp.13005

      • image
      • image
      • image
    4. You have free access to this content
  5. REVIEWS

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have free access to this content
      Therapeutic nucleic acids: current clinical status (pages 659–672)

      Kannan Sridharan and Nithya Jaideep Gogtay

      Version of Record online: 3 JUN 2016 | DOI: 10.1111/bcp.12987

    2. You have free access to this content
    3. Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity (pages 683–695)

      Folefac Aminkeng, Colin J. D. Ross, Shahrad R. Rassekh, Soomi Hwang, Michael J. Rieder, Amit P. Bhavsar, Anne Smith, Shubhayan Sanatani, Karen A. Gelmon, Daniel Bernstein, Michael R. Hayden, Ursula Amstutz, Bruce C. Carleton and CPNDS Clinical Practice Recommendations Group

      Version of Record online: 30 JUN 2016 | DOI: 10.1111/bcp.13008

  6. CLINICAL TRIALS

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have full text access to this OnlineOpen article
      Brentuximab vedotin, an antibody–drug conjugate, in patients with CD30-positive haematologic malignancies and hepatic or renal impairment (pages 696–705)

      Baiteng Zhao, Robert Chen, Owen A. O'Connor, Ajay K. Gopal, Radhakrishnan Ramchandren, Andre Goy, Jeffrey V. Matous, Adedigbo A. Fasanmade, Thomas J. Manley and Tae H. Han

      Version of Record online: 29 MAY 2016 | DOI: 10.1111/bcp.12988

      • image
  7. TRANSLATIONAL RESEARCH

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have free access to this content
      Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers (pages 706–716)

      Bart A. W. Jacobs, Maarten J. Deenen, Dick Pluim, J. G. Coen van Hasselt, Martin D. Krähenbühl, Robin M. J. M. van Geel, Niels de Vries, Hilde Rosing, Didier Meulendijks, Artur M. Burylo, Annemieke Cats, Jos H. Beijnen, Alwin D. R. Huitema and Jan H. M. Schellens

      Version of Record online: 3 JUN 2016 | DOI: 10.1111/bcp.13007

      • image
      • image
      • image
      • image
  8. PHARMACODYNAMICS

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
  9. PHARMACOKINETICS

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have full text access to this OnlineOpen article
      Pharmacokinetics of ixazomib, an oral proteasome inhibitor, in solid tumour patients with moderate or severe hepatic impairment (pages 728–738)

      Neeraj Gupta, Michael J. Hanley, Karthik Venkatakrishnan, Raymond Perez, Robin E. Norris, John Nemunaitis, Huyuan Yang, Mark G. Qian, Gerald Falchook, Richard Labotka and Siqing Fu

      Version of Record online: 29 MAY 2016 | DOI: 10.1111/bcp.12991

      • image
      • image
      • image
    2. Model-based evaluation of pulmonary pharmacokinetics in asthmatic and COPD patients after oral olodaterol inhalation (pages 739–753)

      Jens Markus Borghardt, Benjamin Weber, Alexander Staab, Christina Kunz and Charlotte Kloft

      Version of Record online: 23 JUN 2016 | DOI: 10.1111/bcp.12999

      • image
      • image
      • image
      • image
    3. Salivary caffeine concentrations are comparable to plasma concentrations in preterm infants receiving extended caffeine therapy (pages 754–761)

      Nicole R. Dobson, Xiaoxi Liu, Lawrence M. Rhein, Robert A. Darnall, Michael J. Corwin, Betty L. McEntire, Robert M. Ward, Laura P. James, Catherine M. T. Sherwin, Timothy C. Heeren and Carl E. Hunt

      Version of Record online: 3 JUN 2016 | DOI: 10.1111/bcp.13001

      • image
      • image
      • image
      • image
    4. Population pharmacokinetics and prophylactic anti-emetic efficacy of ramosetron in surgical patients (pages 762–772)

      Yong-Hun Lee, Jae-Hyeon Seo, Kyung-Tae Min, Young-Jin Lim, Seong-Wook Jeong, Eun-Kyung Lee, Byung-Moon Choi and Gyu-Jeong Noh

      Version of Record online: 8 JUN 2016 | DOI: 10.1111/bcp.13010

      • image
      • image
      • image
  10. PHARMACOKINETIC DYNAMIC RELATIONSHIPS

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. Pharmacokinetic–pharmacodynamic modelling of acute N-terminal pro B-type natriuretic peptide after doxorubicin infusion in breast cancer (pages 773–783)

      Shuang Liang, Richard C. Brundage, Pamala A. Jacobson, Anne Blaes and Mark N. Kirstein

      Version of Record online: 3 JUN 2016 | DOI: 10.1111/bcp.12989

      • image
      • image
      • image
      • image
    2. R- and S-citalopram concentrations have differential effects on neuropsychiatric scores in elders with dementia and agitation (pages 784–792)

      Thang Ho, Bruce G. Pollock, Benoit H. Mulsant, Oliver Schantz, Devangere P. Devanand, Jacobo E. Mintzer, Anton P. Porsteinsson, Lon S. Schneider, Daniel Weintraub, Jerome Yesavage, Lea T. Drye, Cynthia A. Munro, David M. Shade, Constantine Lyketsos and Robert Bies

      Version of Record online: 20 JUN 2016 | DOI: 10.1111/bcp.12997

      • image
      • image
      • image
  11. PAEDIATRIC CLINICAL PHARMACOLOGY

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
  12. METHODS IN CLINICAL PHARMACOLOGY

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
  13. DRUG SAFETY

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials (pages 814–822)

      Daniel R. Morales, Tobias Dreischulte, Brian J. Lipworth, Peter T. Donnan, Cathy Jackson and Bruce Guthrie

      Version of Record online: 17 JUN 2016 | DOI: 10.1111/bcp.13006

      • image
      • image
      • image
    2. Statin-induced liver injury in an area endemic for hepatitis B virus infection: risk factors and outcome analysis (pages 823–830)

      Li Yueh Wang, Yi-Shin Huang, Chin-Lin Perng, Bryan Huang and Han-Chieh Lin

      Version of Record online: 17 JUN 2016 | DOI: 10.1111/bcp.13009

      • image
    3. The impact of a medication review with follow-up service on hospital admissions in aged polypharmacy patients (pages 831–838)

      Amaia Malet-Larrea, Estíbaliz Goyenechea, Victoria García-Cárdenas, Begoña Calvo, Jose M. Arteche, Pedro Aranegui, Jose J. Zubeldia, Miguel A. Gastelurrutia, Fernando Martínez-Martínez and Shalom I. Benrimoj

      Version of Record online: 9 JUN 2016 | DOI: 10.1111/bcp.13012

      • image
    4. Risk of venous thromboembolism in cancer patients treated with epoetins or blood transfusions (pages 839–848)

      Antonios Douros, Kathrin Jobski, Bianca Kollhorst, Tania Schink and Edeltraut Garbe

      Version of Record online: 22 JUN 2016 | DOI: 10.1111/bcp.13019

      • image
      • image
  14. PHARMACOEPIDEMIOLOGY

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. Prescribing trends of attention-deficit hyperactivity disorder (ADHD) medications in UK primary care, 1995–2015 (pages 858–868)

      Christel Renoux, Ju-Young Shin, Sophie Dell'Aniello, Emma Fergusson and Samy Suissa

      Version of Record online: 9 JUN 2016 | DOI: 10.1111/bcp.13000

      • image
      • image
      • image
      • image
      • image
      • image
    2. Do patients with intake of drugs labelled as sleep disturbing really sleep worse? A population based assessment from the Heinz Nixdorf Recall Study (pages 869–877)

      Anna-Therese Lehnich, Bernd Kowall, Oliver Kuß, Andrea Schmidt-Pokrzywniak, Gerhard Weinreich, Nico Dragano, Susanne Moebus, Raimund Erbel, Karl-Heinz Jöckel and Andreas Stang

      Version of Record online: 23 JUN 2016 | DOI: 10.1111/bcp.13015

      • image
      • image
      • image
  15. NEW DRUG MECHANISM

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. You have full text access to this OnlineOpen article
      Sofosbuvir and daclatasvir (pages 878–879)

      Marleen H. M. Hessel, Adam F. Cohen and Robert Rissmann

      Version of Record online: 12 JUN 2016 | DOI: 10.1111/bcp.13011

      • image
  16. META-ANALYSIS

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
  17. LETTER TO THE EDITOR

    1. Top of page
    2. ISSUE INFORMATION
    3. ISSUE HIGHLIGHTS
    4. EDITORIAL
    5. SYSTEMATIC REVIEWS
    6. REVIEWS
    7. CLINICAL TRIALS
    8. TRANSLATIONAL RESEARCH
    9. PHARMACODYNAMICS
    10. PHARMACOKINETICS
    11. PHARMACOKINETIC DYNAMIC RELATIONSHIPS
    12. PAEDIATRIC CLINICAL PHARMACOLOGY
    13. METHODS IN CLINICAL PHARMACOLOGY
    14. DRUG SAFETY
    15. PHARMACOEPIDEMIOLOGY
    16. NEW DRUG MECHANISM
    17. META-ANALYSIS
    18. LETTER TO THE EDITOR
    1. Oseltamivir pharmacokinetics in Mexican obese and non-obese healthy subjects and patients. Evidence for an absence of interethnic variability (pages 890–891)

      Gilberto Castañeda-Hernández, Adrián Martínez-Talavera, Lina Marcela Barranco-Garduño, Ariadna Cervantes-Nevárez, Héctor León-Molina, Miriam del Carmen Carrasco-Portugal and Francisco Javier Flores-Murrieta

      Version of Record online: 10 JUN 2016 | DOI: 10.1111/bcp.13003

    2. Statins for primary prevention in practice: clinical use in Wales and the NICE guideline effect (pages 892–894)

      Majd B. Protty, Arron Lacey, Jamie Hayes and Phillip Freeman

      Version of Record online: 3 JUN 2016 | DOI: 10.1111/bcp.13014

SEARCH

SEARCH BY CITATION