A full list of authors is provided in the Supplementary Information.
A common microdeletion affecting a hippocampus- and amygdala-specific isoform of tryptophan hydroxylase 2 is not associated with affective disorders
Article first published online: 23 APR 2014
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Volume 16, Issue 7, pages 764–768, November 2014
How to Cite
MooDS Consortium, , , , , , . A common microdeletion affecting a hippocampus- and amygdala-specific isoform of tryptophan hydroxylase 2 is not associated with affective disorders. Bipolar Disord 2014: 16: 764–768. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd., , , , , , , , ,
- Issue published online: 27 OCT 2014
- Article first published online: 23 APR 2014
- Manuscript Accepted: 11 FEB 2014
- Manuscript Received: 5 JUL 2013
- Medical Faculty of the University of Heidelberg
- German Federal Ministry of Education and Research
- Integrated Genome Research Network (IG) MooDS. Grant Numbers: 01GS08144, 01GS08147
Appendix S1. MooDS Consortium (BPAD and MDD).
Data S1. Supporting methods. Published findings overlapping with the CNP in TPH2 (derived from the Database of Genomic Variants: http://dgv.tcag.ca/dgv/app/home).
Table S1. List of analyzed genes
Table S2. List of primers.
Figure S1. (A) Schematic of the TPH2 gene. The coding sequence of the standard isoform (NM_173353.3) is represented in yellow; the alternative exons 5a and 5b of AK094614 are depicted as blue arrows. The microdeletion is represented as a red arrow. (B) 5′ (left) and 3′ (right) breakpoints of the deletion are shown as determined by sequencing. Due to sequence homology, the exact breakpoints could not be narrowed down to less than 41 bp and are represented in yellow.
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