Bipolar disorder, miscarriage, and termination
Article first published online: 9 JUN 2014
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Volume 17, Issue 1, pages 102–105, February 2015
How to Cite
Bipolar disorder, miscarriage, and termination. Bipolar Disord 2015: 17: 102–105. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd., , , , , .
- Issue published online: 25 JAN 2015
- Article first published online: 9 JUN 2014
- Manuscript Accepted: 27 DEC 2013
- Manuscript Received: 12 JUL 2013
- Cardiff MRC Centre Clinical Academic Mentorship (CAM) Scheme Fellowship
- Wellcome Trust
- Stanley Medical Research Institute
- Medical Research Council
- bipolar disorder;
To compare rates of bipolar episodes following miscarriage and termination with those occurring in the postpartum period.
Information in relation to pregnancy and childbirth was gathered retrospectively for 1,283 women with broadly defined bipolar disorder by interview and case-notes review.
Rates of mania or affective psychosis were significantly higher after full-term delivery than after termination (p < 0.001) or miscarriage (p < 0.001). Rates of non-psychotic major depression were similar following full-term deliveries, miscarriages (p = 0.362), and terminations (p = 0.301).
While women with bipolar disorder and their clinicians should be aware of the possible onset of depression in the weeks following miscarriage or termination, episodes of mania or affective psychosis are less common in comparison with the high rates observed in the postpartum period.