Funding sources This study was funded by the Innovation Oriented Research Program on Genomics (SenterNovem; IGE01014 and IGE5007), the Centre for Medical Systems Biology, the Netherlands Genomics Initiative/Netherlands Organization for Scientific Research (05040202 and 050-060-810), Unilever PLC and the EU-funded Network of Excellence Lifespan (FP6 036894). P.E.S. is supported by an unrestricted grant from the Netherlands Genomics Initiative (NCHA 050-060-810).
CLINICAL AND LABORATORY INVESTIGATIONS
Serum insulin-like growth factor 1 and facial ageing: high levels associate with reduced skin wrinkling in a cross-sectional study
Article first published online: 31 JAN 2013
© 2012 The Authors. BJD © 2012 British Association of Dermatologists
British Journal of Dermatology
Volume 168, Issue 3, pages 533–538, March 2013
How to Cite
Noordam, R., Gunn, D.A., Tomlin, C.C., Maier, A.B., Griffiths, T., Catt, S.D., Ogden, S., Slagboom, P.E., Westendorp, R.G.J., Griffiths, C.E.M., van Heemst, D., de Craen, A.J.M. and on behalf of the Leiden Longevity Study group (2013), Serum insulin-like growth factor 1 and facial ageing: high levels associate with reduced skin wrinkling in a cross-sectional study. British Journal of Dermatology, 168: 533–538. doi: 10.1111/bjd.12131
Conflicts of interest None declared.
- Issue published online: 28 FEB 2013
- Article first published online: 31 JAN 2013
- Accepted for publication 17 October 2012
Figure S1. Comparison of (a) perceived age, (b) wrinkle score and (c) insulin-like growth factor (IGF)-1 to IGF-binding protein (IGFBP)3 ratio between participants mostly staying inside and participants going out regularly.
Table S1. Association of considered confounding factors with perceived age and wrinkle grade.
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