Funding sources None.
Demographic and clinical characteristics of cutaneous lupus erythematosus at a paediatric dermatology referral centre
Article first published online: 13 AUG 2013
© 2013 British Association of Dermatologists
British Journal of Dermatology
Volume 169, Issue 2, pages 428–433, August 2013
How to Cite
Dickey, B.Z., Holland, K.E., Drolet, B.A., Galbraith, S.S., Lyon, V.B., Siegel, D.H. and Chiu, Y.E. (2013), Demographic and clinical characteristics of cutaneous lupus erythematosus at a paediatric dermatology referral centre. British Journal of Dermatology, 169: 428–433. doi: 10.1111/bjd.12383
Conflicts of interest None declared.
- Issue published online: 13 AUG 2013
- Article first published online: 13 AUG 2013
- Accepted manuscript online: 21 APR 2013 10:15PM EST
- Manuscript Accepted: 9 APR 2013
Paediatric cutaneous lupus erythematosus (CLE) is uncommon and inadequately described in the literature. Similar to adults, children with CLE develop LE-specific and/or LE-nonspecific skin findings. Similarities and differences in demographics and clinical course between paediatric and adult CLE have not been sufficiently described.
To detail the demographic and clinical features of paediatric CLE and compare these findings with those reported in the adult literature.
A retrospective chart review was performed of 53 children seen in a paediatric dermatology clinic with cutaneous manifestations of LE.
Patients presented with all five major subtypes of CLE, with some notable differences from adult CLE and previously published reports of paediatric CLE. Progression from discoid LE to systemic LE (SLE) did not occur in our cohort. Patients with subacute CLE were more likely than adults to have lesions below the waist as well as concomitant SLE. Sex distribution for CLE in our study was equal prior to puberty and female predominant in post-pubertal patients.
Children with CLE have variable clinical presentations and progression to SLE that may be different from adult disease. Specifically, children with acute and subacute CLE may be more likely than adults to have systemic disease; therefore, patients with these subtypes should be monitored closely for evidence of SLE. Study limitations included small patient numbers that may limit the ability to generalize these data and relatively short follow-up intervals.