The current status of bridging anticoagulation

Authors

  • Jignesh P. Patel,

    Corresponding author
    1. Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, UK
    2. Institute of Pharmaceutical Science, King's College London, London, UK
    • Correspondence: Jignesh P. Patel, Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK.

      E-mail: jig.patel@kcl.ac.uk

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  • Roopen Arya

    1. Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, UK
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Summary

For patients prescribed chronic vitamin K antagonist therapy requiring a surgical or invasive procedure, the question of whether or not to bridge and how to bridge is commonly encountered in clinical practice. Bridging anticoagulation has evolved over the years and the evidence base for current practice is deficient in many areas. Clinical trials currently being completed with conventional anticoagulants should help strengthen the evidence base for future practice. The availability of novel oral anticoagulants is a welcome addition, though their optimal management peri-procedure is yet to be determined. Prospective multi-centre controlled studies that can provide the evidence base for novel oral anticoagulant peri-procedural management are required.

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