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Keywords:

  • ABO;
  • blood group;
  • blood type;
  • prognosis

Objective

  • To evaluate ABO blood group as a prognostic marker in patients with renal cell carcinoma (RCC).

Patients and Methods

  • This retrospective study included 556 consecutive patients who underwent surgery for RCC at a single institution.
  • The associations of ABO blood group with clinical and pathological variables were assessed using Kruskal–Wallis and chi-squared tests.
  • The impact on overall survival (OS) and RCC-specific survival (RCC-SS) was analysed using univariable and multivariable Cox proportional hazards regression models.

Results

  • Blood group O was associated with the absence of lymph node metastases (P = 0.034) and the presence of bilateral RCC (P = 0.017).
  • No associations with age, gender, body mass index, Charlson comorbidity index, T stage, M stage, grade and histological subtype were observed.
  • In univariable and multivariable survival analysis, ABO blood group was not associated with OS and RCC-SS.

Conclusions

  • In the present study, ABO blood group was not linked with RCC prognosis.
  • Blood group O may be associated with the absence of lymph node metastases and the presence of bilateral RCC.
  • External validation in larger cohorts is necessary.