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bpa12005-sup-0001-figureS1.tif7802K

Figure S1. Negative controls for CD11b and Aβ confocal images. Images were taken at 400× magnification and followed a similar protocol, and were incubated in FITC and Texas Red conjugated secondary antibodies without primary antibody.

bpa12005-sup-0002-figureS2.tif165K

Figure S2. Immunoprecipitation was performed on all target proteins from Figure 3. Western blots for CD11b were done on precipitates of a C3b, b ApoE4, c Aβ40/42 to confirm findings in Figure 3.

bpa12005-sup-0003-figureS3.tif6955K

Figure S3. Negative controls for C5b-9 (MAC) staining on fixed occipital lobe sections. Images were taken at 200× magnification and were prepared using a similar protocol and were incubated in Dylight 550 conjugated secondary antibody without primary antibody. A negative control image for Thioflavin S was taken without staining on the green channel. Scale bar = 200 μm.

bpa12005-sup-0004-figureS4.tif11789K

Figure S4. Representative images of C5b-9 (MAC) staining (red) colocalized with αsma (green) on a cortical arteriole in a case of AD/CAA. Scale bar = 30 μm.

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