The Concise Guide to PHARMACOLOGY 2013/14. This issue was published by Wiley with financial contributions from the British Pharmacological Society, the International Union of Basic and Clinical Pharmacology, the Wellcome Trust (099156/Z/12/Z]), which supports the website, and the University of Edinburgh, who host the guidetopharmacology.org website
The Concise Guide to PHARMACOLOGY 2013/14: Enzymes
Article first published online: 17 DEC 2013
Copyright © 2013 The British Pharmacological Society
British Journal of Pharmacology
Special Issue: The Concise Guide to PHARMACOLOGY 2013/14
Volume 170, Issue 8, pages 1797–1867, December 2013
How to Cite
Alexander, S. P.H., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Spedding, M., Peters, J. A., Harmar, A. J. and CGTP Collaborators (2013), The Concise Guide to PHARMACOLOGY 2013/14: Enzymes. British Journal of Pharmacology, 170: 1797–1867. doi: 10.1111/bph.12451
- Issue published online: 17 DEC 2013
- Article first published online: 17 DEC 2013
- British Pharmacological Society
- International Union of Basic and Clinical Pharmacology
- Wellcome Trust. Grant Number: 099156/Z/12/Z
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full.
Enzymes are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein-coupled receptors, ligand-gated ion channels, ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets.
It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and the Guide to Receptors and Channels, providing a permanent, citable, point-in-time record that will survive database updates.