These authors contributed equally.
A quantitative model of amphetamine action on the 5-HT transporter
Version of Record online: 24 JAN 2014
© 2013 The Authors. British Journal of Pharmacology published by John Wiley &. Sons Ltd on behalf of The British Pharmacological Society.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
British Journal of Pharmacology
Special Issue: Themed Section: Midkine. Guest Editors: Takashi Muramatsu and Kenji Kadomatsu
Volume 171, Issue 4, pages 1007–1018, February 2014
How to Cite
Sandtner, W., Schmid, D., Schicker, K., Gerstbrein, K., Koenig, X., Mayer, F. P., Boehm, S., Freissmuth, M. and Sitte, H. H. (2014), A quantitative model of amphetamine action on the 5-HT transporter. British Journal of Pharmacology, 171: 1007–1018. doi: 10.1111/bph.12520
- Issue online: 24 JAN 2014
- Version of Record online: 24 JAN 2014
- Accepted manuscript online: 20 NOV 2013 03:30AM EST
- Manuscript Accepted: 5 NOV 2013
- Manuscript Revised: 30 OCT 2013
- Manuscript Received: 4 JUL 2013
- Austrian Science Fund/FWF. Grant Numbers: F3506, F3510, P22893-B1
Figure S1 A representative current trace recorded from DAT expressed in a HEK293 cell. The cell was clamped to −70 mV utilizing the whole cell patch clamp technique. The cell was challenged with 100 μM (S+)-amphetamine for 5 s. Upon wash-out of (S+)-amphetamine the current decayed slowly to initial values. However, a persistent current was not observed.
Scheme S1 Cell modelled as a sphere.
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