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Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents (pages 1513–1522)M. J. Field, R. J. Oles, A. S. Lewis, S McCleary, J Hughes and L Singh
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701320
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Effects of Ca2+ channel blocker neurotoxins on transmitter release and presynaptic currents at the mouse neuromuscular junction (pages 1531–1540)Eleonora Katz, Darío A. Protti, Pablo A. Ferro, Marcelo D. Rosato Siri and Osvaldo D. Uchitel
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701290
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Contribution of phosphodiesterase isozymes to the regulation of the L-type calcium current in human cardiac myocytes (pages 1549–1556)Katsuya Kajimoto, Nobuhisa Hagiwara, Hiroshi Kasanuki and Saichi Hosoda
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701297
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Fluoroquinolone (ciprofloxacin) secretion by human intestinal epithelial (Caco-2) cells (pages 1567–1578)M. E. Cavet, M West and N. L. Simmons
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701302
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Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and dogs (pages 1597–1604)Michael Mark and Wolfgang Grell
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701307
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Investigation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat (pages 1613–1618)Helen C. Jackson, M. Clair Bearham, Lisa J. Hutchins, Sarah E. Mazurkiewicz, Andrew M. Needham and David J. Heal
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701311
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Involvement of interleukin-1β, nerve growth factor and prostaglandin E2 in endotoxin-induced localized inflammatory hyperalgesia (pages 1619–1626)Bared Safieh-Garabedian, Salim A. Kanaan, John J. Haddad, Pamela Abou Jaoude, Suhayl J. Jabbur and Nayef E. Saadé
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701313
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Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat (pages 1637–1644)Teresa Iuvone, Nancy Van Osselaer, Fulvio D'Acquisto, Rosa Carnuccio and Arnold G. Herman
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701317
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Induction of neutrophil chemotactic factor production by staurosporine in rat peritoneal neutrophils (pages 1651–1658)Takeo Edamatsu, Yi-Qun Xiao, Jun-ichi Tanabe, Suetsugu Mue and Kazuo Ohuchi
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701322
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The role of cyclic nucleotides in guinea-pig bladder contractility (pages 1665–1672)Penelope A. Longhurst, Janice A K. Briscoe, David J. Rosenberg and Robert E. Leggett
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701328
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Characterization of [3H]-prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virus (pages 1673–1678)Fiona H. Marshall, Kalpana Patel, Kenneth Lundstrom, Janet Camacho, Steven M. Foord and Melanie G. Lee
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701332
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Profile of SB-204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures (pages 1679–1686)Neil Upton, Tom P. Blackburn, Colin A. Campbell, Duncan Cooper, Martyn L. Evans, Hugh J. Herdon, Penny D. King, Alison M. Ray, Tania O. Stean, Wai N. Chan, John M. Evans and Mervyn Thompson
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701330
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Characterization of the binding of [3H]-SB-204269, a radiolabelled form of the new anticonvulsant SB-204269, to a novel binding site in rat brain membranes (pages 1687–1691)Hugh J. Herdon, Jeffrey C. Jerman, Tania O. Stean, Derek N. Middlemiss, Wai N. Chan, Antonio K. Vong, John M. Evans, Mervyn Thompson and Neil Upton
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701331
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Characterization of the signalling pathways involved in ATP and basic fibroblast growth factor-induced astrogliosis (pages 1692–1699)Chiara Bolego, Stefania Ceruti, Roberta Brambilla, Lina Puglisi, Flaminio Cattabeni, Geoffrey Burnstock and Maria P. Abbracchio
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701294
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Characterization of the Ca2+ responses evoked by ATP and other nucleotides in mammalian brain astrocytes (pages 1700–1706)Carlo Centemeri, Chiara Bolego, Maria P. Abbracchio, Flaminio Cattabeni, Lina Puglisi, Geoffrey Burnstock and Simonetta Nicosia
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701293
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Characterization of α2-adrenoceptors mediating contraction of dog saphenous vein: identity with the human α2A subtype (pages 1721–1729)S. J. MacLennan, L. A. Luong, J. R. Jasper, Z. P. To and R. M. Eglen
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701296
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Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro (pages 1730–1734)Shigemi Yoshihara, Anders Lindén, Kazuhisa Kashimoto, Yumiko Nagano, Tohju Ichimura and Jay A. Nadel
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701310
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ATP release and contraction mediated by different P2-receptor subtypes in guinea-pig ileal smooth muscle (pages 1744–1748)Katsuichi Matsuo, Takeshi Katsuragi, Sono Fujiki, Chiemi Sato and Tatsuo Furukawa
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701329
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Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat (pages 1758–1762)Helen C. Jackson, Andrew M. Needham, Lisa J. Hutchins, Sarah E. Mazurkiewicz and David J. Heal
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701312
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Regulation of bradykinin B2-receptor expression by oestrogen (pages 1763–1769)Paolo Madeddu, Costanza Emanueli, Maria Vittoria Varoni, Maria Piera Demontis, Vittorio Anania, Nicola Gorioso and Julie Chao
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701255
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Reduction of urinary 8-epi-prostaglandin F2α during cyclo-oxygenase inhibition in rats but not in man (pages 1770–1774)Angela Bachi, Raffaella Brambilla, Roberto Fanelli, Roberto Bianchi, Ettore Zuccato and Chiara Chiabrando
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701321
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The involvement of tumour necrosis factor-α in the protective effects of 17β oestradiol in splanchnic ischaemia-reperfusion injury (pages 1782–1788)Francesco Squadrito, Domenica Altavilla, Giovanni Squadrito, Giuseppe M. Campo, Mariarita Arlotta, Vincenzo Arcoraci, Letteria Minutoli, Antonino Saitta and Achille P. Caputi
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701288
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Inhibitory effect of a new steroidal saponin, OSW-1, on ovarian functions in rats (pages 1796–1802)Kazuhiro Tamura, Hideo Honda, Yoshihiro Mimaki, Yutaka Sashida and Hiroshi Kogo
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701309
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Catecholamine modulatory effects of nepicastat (RS-25560-197), a novel, potent and selective inhibitor of dopamine-β-hydroxylase (pages 1803–1809)William C. Stanley, Bin Li, Douglas W. Bonhaus, Lowell G. Johnson, Keiho Lee, Seth Porter, Keith Walker, Greg Martinez, Richard M. Eglen, Roger L. Whiting and Sharath S. Hegde
Article first published online: 11 FEB 2009 | DOI: 10.1038/sj.bjp.0701315
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