Effect of miR-122 and its target gene cationic amino acid transporter 1 on colorectal liver metastasis
Version of Record online: 13 MAR 2013
© 2013 Japanese Cancer Association
Volume 104, Issue 5, pages 624–630, May 2013
How to Cite
(Cancer Sci 2013; 104: 624–630)
- Issue online: 15 APR 2013
- Version of Record online: 13 MAR 2013
- Accepted manuscript online: 4 FEB 2013 04:05AM EST
- Manuscript Accepted: 4 FEB 2013
- Manuscript Revised: 14 JAN 2013
- Manuscript Received: 4 OCT 2012
- Ministry of Education, Culture, Sports, Science, and Technology of Japan. Grant Numbers: 22791270, 20670004, 21390376
- Development of System and Technology
Fig. S1. Expression levels of miR-122 in normal colon mucosae, primary colorectal cancers, and colorectal liver metastases of the same six patients by quantitative RT-PCR.
Fig. S2. Correlation between the expression levels of miR-122 and cationic amino acid transporter 1 (CAT1) protein in six colorectal liver metastases.
Fig. S3. Expression levels of cationic amino acid transporter 1 (CAT1) and miR-122 by quantitative RT-PCR in colorectal adenocarcinoma cell lines DLD-1, SW480, and HCT116.
Fig. S4. Liver metastasis-free survival by cationic amino acid transporter 1 (CAT1) positivity in 46 primary colorectal cancers of patients who received adjuvant chemotherapy after surgery for stage II or III colorectal cancer.
|cas12122-sup-0002-DataS1.pdf||application/PDF||103K||Doc. S1. Materials and methods.|
|cas12122-sup-0003-TableS1.xlsx||application/msexcel||12K||Table S1. Top 20 miRNAs up- and downregulated in metachronous liver metastasis compared with primary tumors as assessed by microRNA arrays.|
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.