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Fig. S1. Expression levels of miR-122 in normal colon mucosae, primary colorectal cancers, and colorectal liver metastases of the same six patients by quantitative RT-PCR.

Fig. S2. Correlation between the expression levels of miR-122 and cationic amino acid transporter 1 (CAT1) protein in six colorectal liver metastases.

Fig. S3. Expression levels of cationic amino acid transporter 1 (CAT1) and miR-122 by quantitative RT-PCR in colorectal adenocarcinoma cell lines DLD-1, SW480, and HCT116.

Fig. S4. Liver metastasis-free survival by cationic amino acid transporter 1 (CAT1) positivity in 46 primary colorectal cancers of patients who received adjuvant chemotherapy after surgery for stage II or III colorectal cancer.

cas12122-sup-0002-DataS1.pdfapplication/PDF103KDoc. S1. Materials and methods.
cas12122-sup-0003-TableS1.xlsxapplication/msexcel12KTable S1. Top 20 miRNAs up- and downregulated in metachronous liver metastasis compared with primary tumors as assessed by microRNA arrays.

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