These authors contributed equally to this work.
Tumor-suppressive microRNA-143/145 cluster targets hexokinase-2 in renal cell carcinoma
Version of Record online: 11 OCT 2013
© 2013 Japanese Cancer Association
Volume 104, Issue 12, pages 1567–1574, December 2013
How to Cite
(Cancer Sci 2013; 104: 1567–1574)
- Issue online: 6 DEC 2013
- Version of Record online: 11 OCT 2013
- Accepted manuscript online: 6 SEP 2013 09:20AM EST
- Manuscript Accepted: 31 AUG 2013
- Manuscript Revised: 19 AUG 2013
- Manuscript Received: 5 JUN 2013
- Ministry of Education, Sciences, Sports, and Culture of Japan
- Science Research (B and C). Grant Numbers: 23501298, 23592340
|cas12280-sup-0001-FigS1.TIF||image/tif||554K||Fig. S1. Effects of miR-143 and miR-145 transfection on 786-O and A498 renal cell carcinoma cells. Suppression effects of 786-O and A498 cell proliferation after transfection with miR-143, miR-145, and cotransfection of miR-143 and miR-145 as determined by XTT assay. *P < 0.0005; **P < 0.0001.|
|cas12280-sup-0002-FigS2.TIF||image/tif||518K||Fig. S2. Inverse correlations between hexokinase-2 (HK2) mRNA and miR-143 or miR-145 expression in RCC clinical specimens.|
Table S1. Patient characteristics.
Table S2. Insert sequences of wild-type and deletion vectors for luciferase assay.
Table S3. Last 49 highly expressed genes regulated by the putative targets miR-143 and miR-145 in clinical renal cell carcinoma specimens.
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