Traditional Chinese Medicine Science Research Funds Program of Zhejiang (2013ZA077); Natural Science Funds of Zhejiang (Y2110555); National 973 Basic Research Program of China (2013CB911300).
N1-guanyl-1,7-diaminoheptane sensitizes bladder cancer cells to doxorubicin by preventing epithelial–mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2 activation
Article first published online: 7 JAN 2014
© 2013 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Volume 105, Issue 2, pages 219–227, February 2014
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How to Cite
Cancer Sci 105 (2014) 219–227
- Issue published online: 10 FEB 2014
- Article first published online: 7 JAN 2014
- Accepted manuscript online: 22 NOV 2013 12:14AM EST
- Manuscript Accepted: 17 NOV 2013
- Manuscript Revised: 11 NOV 2013
- Manuscript Received: 14 JUL 2013
- Traditional Chinese Medicine Science Research Funds Program of Zhejiang. Grant Number: 2013ZA077
- Natural Science Funds of Zhejiang. Grant Number: Y2110555
- National 973 Basic Research Program of China. Grant Number: 2013CB911300
|cas12328-sup-0001-FigS1.tif||image/tif||587K||Fig. S1. Effects of transfection of negative control siRNA on cytotoxicity and phenotype transition in bladder cancer cells. The cell viability and expression pattern of epithelial–mesenchymal transition markers were tested after 48 h incubation in control (Ctrl) or negative control siRNA (siRNA) transfected bladder cancer cells. Transfection of siRNA per se did not exert any effects on the cell viability (A) (all three bladder cancer cell lines, Ctrl versus siRNA, P > 0.05) or expression levels of epithelial–mesenchymal transition markers (B).|
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