Mesenchymal-transitioned cancer cells instigate the invasion of epithelial cancer cells through secretion of WNT3 and WNT5B
Article first published online: 29 JAN 2014
© 2013 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.
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Volume 105, Issue 3, pages 281–289, March 2014
How to Cite
Cancer Sci 105 (2014) 281–289
Grants-in-aid for Challenging Exploratory Research (24659348) and Grant-in-aid for Young Scientists (B) (24700971) from Ministry of Education, Culture, Sports, Science, and Technology, Japan. Grant-in-Aid for JSPS Fellows (DC2) (2510159) from Japan Society for the Promotion of Science, Japan.
- Issue published online: 6 MAR 2014
- Article first published online: 29 JAN 2014
- Accepted manuscript online: 17 DEC 2013 09:17AM EST
- Manuscript Accepted: 12 DEC 2013
- Manuscript Revised: 10 DEC 2013
- Manuscript Received: 8 NOV 2013
- Ministry of Education, Culture, Sports, Science, and Technology, Japan. Grant Numbers: 24659348, 24700971
- Japan Society for the Promotion of Science, Japan. Grant Number: 2510159
|cas12336-sup-0001-FigS1.TIF||image/tif||825K||Fig. S1. Expression of epithelial-to-mesenchymal transition (EMT)-related proteins following transforming growth factor (TGF-β-induced EMT.|
|cas12336-sup-0002-FigS2.TIF||image/tif||749K||Fig. S2. Effect of seeded cell number on invasion potential in E-cells.|
|cas12336-sup-0003-FigS3.TIF||image/tif||935K||Fig. S3. Quantification of western blotting bands related to Fig. 2 by densitometry.|
|cas12336-sup-0004-FigS4.TIF||image/tif||1115K||Fig. S4. mRNA expression of WNT3 and WNT5B upon siRNA and transforming growth factor (TGF-β treatment.|
|cas12336-sup-0005-FigS5.TIF||image/tif||1827K||Fig. S5. Quantification of western blotting bands related to Fig. 4a and c by densitometry.|
|cas12336-sup-0006-TableS1.xlsx||application/msexcel||13K||Table S1. Common upregulated genes (top 5%) in both mesenchymal-transitioned A549 and Panc-1 cells by the stimulation of transforming growth factor (TGF-β for 7 and 48 h, respectively.|
|cas12336-sup-0007-TableS2.xlsx||application/msexcel||11K||Table S2. Enriched pathways in transforming growth factor (TGF--treated cells.|
|cas12336-sup-0008-DataS1.TIF||image/tif||1835K||Data S1. Materials and Methods.|
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