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cas12351-sup-0001-FigS1ab.tiffTIFF image632KFig. S1. Upregulation of microRNA-16 (miR-16) induced early apoptosis in the human glioma cell lines SHG44, U87 and U373. (A–C) Proportion of apoptotic cells, as determined by flow cytometry (A:SHG44, B:U87, C:U373). (D–F) Each bar represents mean values ± SD from three independent experiments. Asterisk P < 0.05; double asterisk < 0.01(D:SHG44, E:U87, F:U373).
cas12351-sup-0002-FigS1c-f.tiffTIFF image1109K 
cas12351-sup-0003-FigS2.tiffTIFF image354KFig. S2. Transfection efficiency. A, Green fluorescence could be observed in the human glioma cell lines SHG44, U87 and U373. B, The transfection rates in human glioma cell lines SHG44, U87 and U373 were 64.0%, 74.9% and 87.9% respectively, as determined by flow cytometry.

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