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Cancer Science

Cover image for Vol. 103 Issue 2

February 2012

Volume 103, Issue 2

Pages Feb cover–Feb cover, i–iii, 155–392

  1. COVER IMAGE

    1. Top of page
    2. COVER IMAGE
    3. Preliminary Page
    4. In This Issue
    5. ORIGINAL ARTICLES
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      Small non-mucinous bronchioloalveolar carcinoma (BAC) with ALK immunoreactivity. Immunohistochemistry for ALK showing strong expression in the cytoplasm of small non-mucinous BAC cells. (page Feb cover)

      Morio Yamamoto, Kengo Takeuchi, Masaki Shimoji, Tomohiro Maniwa, Mitsuhiro Isaka, Kazuo Nakagawa, Yasuhisa Ohde, Haruhiko Kondo and Takashi Nakajima

      Article first published online: 1 FEB 2012 | DOI: 10.1111/j.1349-7006.2011.02188.x

  2. Preliminary Page

    1. Top of page
    2. COVER IMAGE
    3. Preliminary Page
    4. In This Issue
    5. ORIGINAL ARTICLES
    1. You have full text access to this Open Access content
      Preliminary Page (pages i–ii)

      Article first published online: 1 FEB 2012 | DOI: 10.1111/j.1349-7006.2011.02068.x

  3. In This Issue

    1. Top of page
    2. COVER IMAGE
    3. Preliminary Page
    4. In This Issue
    5. ORIGINAL ARTICLES
    1. You have full text access to this Open Access content
      In this Issue (page iii)

      Article first published online: 21 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02172.x

  4. ORIGINAL ARTICLES

    1. Top of page
    2. COVER IMAGE
    3. Preliminary Page
    4. In This Issue
    5. ORIGINAL ARTICLES
    1. BASIC AND CLINICAL IMMUNOLOGY

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    2. CARCINOGENESIS

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      Prevalence of human papillomavirus in mobile tongue cancer with particular reference to young patients (pages 161–168)

      Masayuki Kabeya, Reiko Furuta, Kazuyoshi Kawabata, Sugata Takahashi and Yuichi Ishikawa

      Article first published online: 15 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02149.x

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      Tumor suppressor p16INK4a controls oncogenic K-Ras function in human pancreatic cancer cells (pages 169–175)

      Anja Rabien, Hugo Sanchez-Ruderisch, Petra Schulz, Noreen Otto, Anja Wimmel, Bertram Wiedenmann and Katharina M. Detjen

      Article first published online: 15 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02140.x

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      Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer (pages 176–180)

      Tetsuya Fujimura, Satoru Takahashi, Tomohiko Urano, Toshiya Tanaka, Weiguang Zhang, Kotaro Azuma, Kenich Takayama, Daisuke Obinata, Taro Murata, Kuniko Horie-Inoue, Tatsuhiko Kodama, Yasuyoshi Ouchi, Yukio Homma and Satoshi Inoue

      Article first published online: 27 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02143.x

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      Notch1 promotes glioma cell migration and invasion by stimulating β-catenin and NF-κB signaling via AKT activation (pages 181–190)

      Xiaohua Zhang, Tao Chen, Jiannan Zhang, Qin Mao, Shanquan Li, Wenhao Xiong, Yongming Qiu, Qiuling Xie and Jianwei Ge

      Article first published online: 15 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02154.x

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      Novel pathway of centrosome amplification that does not require DNA lesions (pages 191–196)

      Masataka Tsuda, Masakazu Tanaka, Masatoshi Mushiake, Jun Takahashi, Koji Tanaka, Joji Watase, Jun-Ichi Fujisawa and Masanao Miwa

      Article first published online: 15 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02152.x

    7. CELL, MOLECULAR, AND STEM CELL BIOLOGY

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      Critical role of CD40-mediated autocrine tumor necrosis factor-alpha in potentiation of cisplatin-induced cytotoxicity in cancer cells (pages 197–202)

      Hong Sun, Ying-Jia Zhong, Xue-Lian Zheng, Qiong Wang, Lan Yang, Fang Shi, Jia-Qi Yan, Fan He, Lin-Chuan Liao, Yong Lin, Lin Zhang and Xia Wang

      Article first published online: 17 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02122.x

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      ZDHHC8 knockdown enhances radiosensitivity and suppresses tumor growth in a mesothelioma mouse model (pages 203–209)

      Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Yuriko Ogawa, Masashi Sagara and Tsuneo Saga

      Article first published online: 20 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02126.x

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      Subtype-specific alterations of the Wnt signaling pathway in breast cancer: Clinical and prognostic significance (pages 210–220)

      Nupur Mukherjee, Nilanjana Bhattacharya, Neyaz Alam, Anup Roy, Susanta Roychoudhury and Chinmay K. Panda

      Article first published online: 7 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02131.x

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      Integrated analysis of whole genome exon array and array-comparative genomic hybridization in gastric and colorectal cancer cells (pages 221–227)

      Kazuyuki Furuta, Tokuzo Arao, Kazuko Sakai, Hideharu Kimura, Tomoyuki Nagai, Daisuke Tamura, Keiichi Aomatsu, Kanae Kudo, Hiroyasu Kaneda, Yoshihiko Fujita, Kazuko Matsumoto, Yasuhide Yamada, Kazuyoshi Yanagihara, Masaru Sekijima and Kazuto Nishio

      Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02132.x

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      Plasminogen activator inhibitor 1 RNAi suppresses gastric cancer metastasis in vivo (pages 228–232)

      Nobuaki Nishioka, Tasuku Matsuoka, Masakazu Yashiro, Kosei Hirakawa, Kenneth Olden and John D. Roberts

      Article first published online: 9 JAN 2012 | DOI: 10.1111/j.1349-7006.2011.02155.x

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      Nucleostemin and TWIST as predictive markers for recurrence after neoadjuvant chemotherapy for esophageal carcinoma (pages 233–238)

      Takako E. Nakajima, Hiroshi Yoshida, Naoko Okamoto, Kengo Nagashima, Hirokazu Taniguchi, Yasuhide Yamada, Tadakazu Shimoda and Kenkichi Masutomi

      Article first published online: 8 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02142.x

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      Mitochondrial transcription factor A regulates BCL2L1 gene expression and is a prognostic factor in serous ovarian cancer (pages 239–444)

      Tomoko Kurita, Hiroto Izumi, Seiji Kagami, Toshinori Kawagoe, Naoyuki Toki, Yusuke Matsuura, Toru Hachisuga and Kimitoshi Kohno

      Article first published online: 23 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02156.x

    14. CLINICAL RESEARCH

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      Central nervous system event in patients with diffuse large B-cell lymphoma in the rituximab era (pages 245–251)

      Naoto Tomita, Masahiro Yokoyama, Wataru Yamamoto, Reina Watanabe, Yutaka Shimazu, Yasufumi Masaki, Saburo Tsunoda, Chizuko Hashimoto, Kayoko Murayama, Takahiro Yano, Rumiko Okamoto, Ako Kikuchi, Kazuo Tamura, Kazuya Sato, Kazutaka Sunami, Hirohiko Shibayama, Rishu Takimoto, Rika Ohshima, Yoshihiro Hatta, Yukiyoshi Moriuchi, Tomohiro Kinoshita, Masahide Yamamoto, Ayumi Numata, Yoshiaki Ishigatsubo and Kengo Takeuchi

      Article first published online: 29 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02139.x

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      Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers (pages 252–261)

      Hirokazu Ohashi, Yasushi Adachi, Hiroyuki Yamamoto, Hiroaki Taniguchi, Katsuhiko Nosho, Hiromu Suzuki, Yoshiaki Arimura, Kohzoh Imai, David P. Carbone and Yasuhisa Shinomura

      Article first published online: 13 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02138.x

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      IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma (pages 269–273)

      Qi SongTao, Yu Lei, Gui Si, Ding YanQing, Han HuiXia, Zhang XueLin, Wu LanXiao and Yao Fei

      Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02134.x

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      Validation and comparison of models to predict non-sentinel lymph node metastasis in breast cancer patients (pages 274–281)

      Kai Chen, Liling Zhu, Weijuan Jia, Nanyan Rao, Miaojing Fan, Hui Huang, Quanyuan Shan, Jingjing Han, Erwei Song, Yunjie Zeng and Fengxi Su

      Article first published online: 8 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02148.x

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      Aclarubicin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis through death receptor 5 upregulation (pages 282–287)

      Mano Horinaka, Tatsushi Yoshida, Susumu Nakata, Takumi Shiraishi, Mitsuhiro Tomosugi, Sae Yoshikawa, Miki Wakada and Toshiyuki Sakai

      Article first published online: 13 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02150.x

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      Phase II multicenter, randomized, double-blind study of recombinant mutated human tumor necrosis factor-α in combination with chemotherapies in cancer patients (pages 288–295)

      Meng Li, Tianjiao Xu, Zhao Zhang, Xiaochang Xue, Cun Zhang, Xin Qin, Weina Li, Qiang Hao, Wei Zhang and Yingqi Zhang

      Article first published online: 9 JAN 2012 | DOI: 10.1111/j.1349-7006.2011.02153.x

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      Mutational complex genotype of the hepatitis B virus X /precore regions as a novel predictive marker for hepatocellular carcinoma (pages 296–304)

      Jeong Won Jang, Ji-Yong Chun, Young Min Park, Soo-Kyung Shin, Wangdon Yoo, Soo-Ok Kim and Sun Pyo Hong

      Article first published online: 19 JAN 2012 | DOI: 10.1111/j.1349-7006.2011.02170.x

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      Notch1 receptor as a marker of lymph node metastases in papillary thyroid cancer (pages 305–309)

      Hyung Seok Park, Chan-Kwon Jung, Sung Hak Lee, Byung Joo Chae, Dong Jun Lim, Woo Chan Park, Byung Joo Song, Jeong Soo Kim, Sang Seol Jung and Ja-Seong Bae

      Article first published online: 16 JAN 2012 | DOI: 10.1111/j.1349-7006.2011.02161.x

    23. DRUG DISCOVERY AND DELIVERY

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    24. You have full text access to this Open Access content
      Direct inhibition of the transforming growth factor-β pathway by protein-bound polysaccharide through inactivation of Smad2 signaling (pages 317–324)

      Yoshihiro Ono, Tetsu Hayashida, Ayano Konagai, Hiroshi Okazaki, Kazuhiro Miyao, Shigeyuki Kawachi, Minoru Tanabe, Masahiro Shinoda, Hiromitsu Jinno, Hirotoshi Hasegawa, Masaki Kitajima and Yuko Kitagawa

      Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02133.x

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      Salmonella-mediated tumor-targeting TRAIL gene therapy significantly suppresses melanoma growth in mouse model (pages 325–333)

      Jianxiang Chen, Bingya Yang, Xiawei Cheng, Yiting Qiao, Bo Tang, Guo Chen, Jing Wei, Xiufeng Liu, Wei Cheng, Pan Du, Xiaofeng Huang, Wenhui Jiang, Qingang Hu, Yiqiao Hu, Jiahuang Li and Zi-Chun Hua

      Article first published online: 15 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02147.x

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      Mechanisms of ellipticine-mediated resistance in UKF-NB-4 neuroblastoma cells (pages 334–341)

      Pavel Procházka, Antonín Libra, Zuzana Zemanová, Jana Hřebačková, Jitka Poljaková, Jan Hraběta, Martin Bunček, Marie Stiborová and Tomáš Eckschlager

      Article first published online: 29 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02137.x

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      Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers (pages 342–349)

      Naomi Ono, Toshikazu Yamazaki, Yoshito Nakanishi, Toshihiko Fujii, Kiyoaki Sakata, Yukako Tachibana, Atsushi Suda, Kihito Hada, Takaaki Miura, Shigeo Sato, Ryoichi Saitoh, Kohnosuke Nakano, Takuo Tsukuda, Toshiyuki Mio, Nobuya Ishii, Osamu Kondoh and Yuko Aoki

      Article first published online: 13 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02144.x

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      Isolation of human mAbs that directly modulate FMS-related tyrosine kinase 3 signaling (pages 350–359)

      Yukiya Yamamoto, Sachiko Tsuzuki, Yasushi Akahori, Yoshinori Ukai, Mariko Sumitomo, Yuko Murayama, Kiyoko Yamamoto, Youko Inaguma, Masutaka Tokuda, Akihiro Abe, Yoshiki Akatsuka, Nobuhiko Emi and Yoshikazu Kurosawa

      Article first published online: 5 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02141.x

    29. EPIDEMIOLOGY AND PREVENTION

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      Trend analysis of cancer incidence in Japan using data from selected population-based cancer registries (pages 360–368)

      Kota Katanoda, Wakiko Ajiki, Tomohiro Matsuda, Yoshikazu Nishino, Akiko Shibata, Manabu Fujita, Hideaki Tsukuma, Akiko Ioka, Midori Soda and Tomotaka Sobue

      Article first published online: 15 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02145.x

    30. INFLAMMATION AND VIROLOGY

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      Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth (pages 369–374)

      Manami Yoshita, Masaya Higuchi, Masahiko Takahashi, Masayasu Oie, Yuetsu Tanaka and Masahiro Fujii

      Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02123.x

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      Antitumor activities of valproic acid on Epstein–Barr virus-associated T and natural killer lymphoma cells (pages 375–381)

      Seiko Iwata, Takashi Saito, Yoshinori Ito, Maki Kamakura, Kensei Gotoh, Jun-ichi Kawada, Yukihiro Nishiyama and Hiroshi Kimura

      Article first published online: 22 NOV 2011 | DOI: 10.1111/j.1349-7006.2011.02127.x

    32. PATHOLOGY

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      Correlation of L-type amino acid transporter 1 and CD98 expression with triple negative breast cancer prognosis (pages 382–389)

      Mio Furuya, Jun Horiguchi, Hiroki Nakajima, Yoshikatsu Kanai and Tetsunari Oyama

      Article first published online: 15 DEC 2011 | DOI: 10.1111/j.1349-7006.2011.02151.x

    33. CASE REPORT

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      Small non-mucinous bronchioloalveolar carcinoma with anaplastic lymphoma kinase immunoreactivity: A novel ALK fusion gene? (pages 390–392)

      Morio Yamamoto, Kengo Takeuchi, Masaki Shimoji, Tomohiro Maniwa, Mitsuhiro Isaka, Kazuo Nakagawa, Yasuhisa Ohde, Haruhiko Kondo and Takashi Nakajima

      Article first published online: 1 FEB 2012 | DOI: 10.1111/j.1349-7006.2011.02136.x

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