SEARCH

SEARCH BY CITATION

References

  • 1
    Noren-Muller A., Reis-Correa I. Jr, Prinz H., Rosenbaum C., Saxena K., Schwalbe H.J., Vestweber D., Cagna G., Schunk S., Schwarz O., Schiewe H., Waldmann H. (2006) Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci USA;103:1060610611.
  • 2
    Tan G., Gyllenhaal C., Soejarto D.D. (2006) Biodiversity as a source of anticancer drugs. Curr Drug Targets;7:265277.
  • 3
    Koch M.A., Schuffenhauer A., Scheck M., Wetzel S., Casaulta M., Odermatt A., Ertl P., Waldmann H. (2005) Charting biologically relevant chemical space: a structural classification of natural products (SCONP). Proc Natl Acad Sci USA;102:1727217277.
  • 4
    Simmons T.L., Andrianasolo E., McPhail K., Flatt P., Gerwick W.H. (2005) Marine natural products as anticancer drugs. Mol Cancer Ther;4:333342.
  • 5
    Clardy J., Walsh C. (2004) Lessons from natural molecules. Nature;432:829837.
  • 6
    Casero R.A. Jr, Marton L.J. (2007) Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases. Nat Rev Drug Discovery;6:373390.
  • 7
    Seiler N. (2005) Pharmacological aspects of cytotoxic polyamine analogs and derivatives for cancer therapy. Pharmacol Ther;107:99119.
  • 8
    Jiang X.J., Yeung S.L., Lo P.C., Fong W.P., Ng D.K.P. (2011) Phthalocyanine-polyamine conjugates as highly efficient photosensitizers for photodynamic therapy. J Med Chem;54:320330.
  • 9
    Battaglia A., Guerrini A., Baldelli E., Fontana G., Varchi G., Samorì C., Bombardelli E. (2006) Synthesis of 7- and 10-spermine conjugates of paclitaxel and 10-deacetylpaclitaxel as potential prodrugs. Tetrahedron Lett;47:26672670.
  • 10
    Chadwick J., Jones M., Mercer A.E., Stocks P.A., Ward S.A., Park B.K., O’Neill P.M. (2010) Design, synthesis and antimalarial/anticancer evaluation of spermidine linked artemisinin conjugates designed to exploit polyamine transporters in Plasmodium falciparum and HL-60 cancer cell lines. Bioorg Med Chem;18:25862597.
  • 11
    Kruczynski A., Vandenberghe I., Pillon A., Pesnel S., Goetsch L., Barret J.M., Guminski Y., Le Pape A., Imbert T., Bailly C., Guilbaud N. (2011) Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system. Invest New Drugs;29:921.
  • 12
    Wang Y., Zhang X., Zhao J., Xie S., Wang C. (2012) Nonhematotoxic naphthalene diimide modified by polyamine: synthesis and biological evaluation. J Med Chem;55:35023512.
  • 13
    Fan J.T., Kuang B., Zeng G.Z., Zhao S.M., Ji C.J., Zhang Y.M., Tan N.H. (2011) Biologically active arborinane-type triterpenoids and anthraquinones from Rubia yunnanensis. J Nat Prod;74:20692080.
  • 14
    Gomez-Monterrey I., Campiglia P., Aquino C., Bertamino A., Granata I., Carotenuto A., Brancaccio D., Stiuso P., Scognamiglio I., Rusciano M.R., Maione A.S., Illario M., Grieco P., Maresca B., Novellino E. (2011) Design, synthesis, and cytotoxic evaluation of acyl derivatives of 3-aminonaphtho[2,3-b]thiophene-4,9-dione, a quinone-based system. J Med Chem;54:40774091.
  • 15
    Mansour O.C., Evison B.J., Sleebs B.E., Watson K.G., Nudelman A., Rephaeli A., Buck D.P., Collins J.G., Bilardi R.A., Phillips D.R., Cutts S.M. (2010) New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation. J Med Chem;53:68516866.
  • 16
    Wang C., Delcros J.G., Cannon L., Konate F., Carias H., Biggerstaff J., Gardner R.A., Phanstiel O. (2003) Defining the molecular requirements for the selective delivery of polyamine conjugates into cells containing active polyamine transporters. J Med Chem;46:51295138.
  • 17
    Gardner R.A., Delcros J.G., Konate F., Breitbeil F., Martin B., Sigman M., Huang M., Phanstiel O. (2004) N 1-substituent effects in the selective delivery of polyamine conjugates into cells containing active polyamine transporters. J Med Chem;47:60556069.
  • 18
    Phanstiel O., Kaur N., Delcros J.G. (2007) Structure-activity investigations of polyamine-anthracene conjugates and their uptake via polyamine transporter. Amino Acids;33:305313.
  • 19
    Wang J., Chen Z., Xie S., Zhao J., Wang C. (2010) Synthesis and bioevaluation of aryl-guanidino polyamine conjugates targeting the polyamine transporter. Bioorg Med Chem Lett;20:64216425.
  • 20
    Bolognesi M.L., Calonghi N., Mangano C., Masotti L., Melchiorre C. (2008) Parallel synthesis and cytotoxicity evaluation of a polyamine-quinone conjugates library. J Med Chem;51:54635467.
  • 21
    Calonghi N., Pagnotta E., Parolin C., Mangano C., Bolognesi M.L., Melchiorre C., Masotti L. (2007) A new EGFR inhibitor induces apoptosis in colon cancer cells. Biochem Biophys Res Commun;354:409413.
  • 22
    Getautis V., Dashkyavichene M., Paulauskaite I., Stanisauskaite A. (2005) Study of the products from reaction of 1(2)-aminoanthraquinones with 1-chloro-2,3-epoxypropane. Chem Heterocycl Compd;41:426436.
  • 23
    Chong H.S., Torti S.V., Ma R., Torti F.M., Brechbiel M.W. (2004) Synthesis and potent antitumor activities of novel 1,3,5-cis,cis-triaminocyclohexane N-pyridyl derivatives. J Med Chem;47:52305234.
  • 24
    Jasys V.J., Kelbaugh P.R., Nason D.M., Phillips D., Rosnack K.J., Saccomano N.A., Stroh J.G., Volkmann R.A., Forman J.T. (1992) Novel quaternary ammonium salt-containing polyamines from the Agelenopsis aperta funnel-web spider. J Org Chem;57:18141820.
  • 25
    Barron G.A., Bermano G., Gordon A., Lin P.K.T. (2010) Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells. Eur J Med Chem;45:14301437.
  • 26
    Chen Z., Liang X., Zhang H., Xie H., Liu J., Xu Y., Zhu W., Wang Y., Wang X., Tan S., Kuang D., Qian X. (2010) A new class of naphthalimide-based antitumor agents that inhibit topoisomerase II and induce lysosomal membrane permeabilization and apoptosis. J Med Chem;53:25892600.
  • 27
    Repnik U., Turk B. (2010) Lysosomal-mitochondrial cross-talk during cell death. Mitochondrion;10:662669.
  • 28
    Yamashima T., Oikawa S. (2009) The role of lysosomal rupture in neuronal death. Prog Neurobiol;89:343358.
  • 29
    Amelio M.D., Cavalluccil V., Cecconi F. (2010) Neuronal caspase-3 signaling: not only cell death. Cell Death Differ;17:11041114.
  • 30
    Quaquebeke E.V., Mahieu T., Dumont P., Dewelle J., Ribaucour F., Simon G., Sauvage S., Gaussin J.F., Tuti J., Yazidi M.E., Vynckt F.V., Mijatovic T., Lefranc F., Darro F., Kiss R. (2007) 2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de] isoquinolin-5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity. J Med Chem;50:41224134.
  • 31
    Indran I.R., Tufo G., Pervaiz S., Brenner C. (2011) Recent advances in apoptosis, mitochondria and drug resistance in cancer cells. Biochimica Biophysica Acta;180:77357745.