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Figure S1. Characterization of hQC WT and selected protein variants by SDS-PAGE.

Table S1. EAB values [in eV] for the amino acids in the active site of either mQC or hQC bound with PBD150.

Table S2. Calculated QMScores and inhibition constants for inhibitors of hQC, representing key compounds of the SAR of PBD150.

Table S3. Calculated QMScores and inhibition constants for inhibitors of mQC.

Table S4. Ki values of the examined mutants and hQC WT.

Table S5. Oligonucleotides applied for cloning, mutation and expression of hQC.

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CBDD_12046_sm_TableS1-S5-FigS1.docx112KSupporting info item

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