Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L
Article first published online: 9 OCT 2012
© 2012 John Wiley & Sons A/S
Chemical Biology & Drug Design
Volume 80, Issue 6, pages 971–980, December 2012
How to Cite
Basavapathruni, A., Jin, L., Daigle, S. R., Majer, C. R. A., Therkelsen, C. A., Wigle, T. J., Kuntz, K. W., Chesworth, R., Pollock, R. M., Scott, M. P., Moyer, M. P., Richon, V. M., Copeland, R. A. and Olhava, E. J. (2012), Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L. Chemical Biology & Drug Design, 80: 971–980. doi: 10.1111/cbdd.12050
- Issue published online: 25 OCT 2012
- Article first published online: 9 OCT 2012
- Accepted manuscript online: 15 SEP 2012 02:40AM EST
- Received 20 April 2012, revised 3 July 2012 and accepted for publication 3 August 2012
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