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Figure S1. Alignment of the predicted TbPTP1secondary model versus the derived crystallographic structure.

Figure S2. TbPTP1 dose-response curvesfor the different PTP1B inhibitors.

Figure S3. PTP1B dose-response curves for thedifferent PTP1B inhibitors.

Figure S4. TbPTP1 competition assayswith the different PTP1B inhibitors.

Figure S5. Comparative summary of the type ofinhibitors tested for TbPTP1 and human PTP1B.

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