Identification of Dipeptidyl Peptidase IV Inhibitors: Virtual Screening, Synthesis and Biological Evaluation
Version of Record online: 14 MAY 2014
© 2014 John Wiley & Sons A/S
Chemical Biology & Drug Design
Volume 84, Issue 3, pages 364–377, September 2014
How to Cite
Xing, J., Li, Q., Zhang, S., Liu, H., Zhao, L., Cheng, H., Zhang, Y., Zhou, J. and Zhang, H. (2014), Identification of Dipeptidyl Peptidase IV Inhibitors: Virtual Screening, Synthesis and Biological Evaluation. Chemical Biology & Drug Design, 84: 364–377. doi: 10.1111/cbdd.12327
- Issue online: 8 AUG 2014
- Version of Record online: 14 MAY 2014
- Accepted manuscript online: 27 MAR 2014 02:16PM EST
- Manuscript Revised: 14 MAR 2014
- Manuscript Accepted: 14 MAR 2014
- Manuscript Received: 9 JAN 2014
- China National Key Hi-Tech Innovation Project. Grant Number: 2013ZX09301303-002
Figure S1. Chemical structures of 18 testing set compounds.
Figure S2. The difference in costs between HypoGen runs and the scrambled runs. The 95% confidence level was selected.
Table S1. Results of top 10 pharmacophore hypotheses of DPP-IV inhibitors generated using training set.
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