Dietary long chain n-3 polyunsaturated fatty acids prevent allergic sensitization to cow's milk protein in mice
Version of Record online: 21 JUN 2013
© 2013 John Wiley & Sons Ltd
Clinical & Experimental Allergy
Volume 43, Issue 7, pages 798–810, July 2013
How to Cite
Clinical & Experimental Allergy, 2013; (43)798–810., , , , , , .
- Issue online: 21 JUN 2013
- Version of Record online: 21 JUN 2013
- Accepted manuscript online: 5 MAR 2013 12:39PM EST
- Manuscript Accepted: 6 FEB 2013
- Manuscript Revised: 5 FEB 2013
- Manuscript Received: 17 SEP 2012
|cea12111-sup-0001-FigS1.pdf||application/PDF||30K||Figure S1. Effect of the fish oil diet on total Th1 and Th2 cell subsets in mesenteric lymph nodes (MLN) and spleen by flow cytometry. The percentage of CD4+ cells in MLN (diet NS, sensitization NS, interaction NS) and spleen (diet P < 0.05, sensitization NS, interaction P = 0.09 for spleen) were not reduced by the fish oil diet. The percentage of total Th1 cells (CD4+CXCR3+) was reduced by the fish oil diet in spleen of sham mice (diet P < 0.01, sensitization NS, interaction NS). Percentages of Th1 cells in MLN showed a similar tendency (diet P < 0.05, sensitization NS, interaction NS) as well as the percentage of total Th2 cells (CD4+T1/ST2+) in spleen (P < 0.01, sensitization NS, interaction NS) and MLN (diet NS, sensitization NS, interaction NS). Data are presented as means ± SEM, n = 6/group. *P < 0.05 two-way anova followed by Bonferroni's multiple comparison test. NS = not significant.|
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