Conflict of interest: none declared.
Clinical dermatology ● Concise report
Multiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy
Article first published online: 13 AUG 2013
© 2013 British Association of Dermatologists
Clinical and Experimental Dermatology
Volume 38, Issue 8, pages 857–861, December 2013
How to Cite
Hunt, W. T., Cameron, A., Craig, P. and de Berker, D. A. (2013), Multiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy. Clinical and Experimental Dermatology, 38: 857–861. doi: 10.1111/ced.12149
- Issue published online: 20 NOV 2013
- Article first published online: 13 AUG 2013
- Manuscript Accepted: 9 JAN 2013
Multiple periungual Bowen disease [BD; also known as squamous cell carcinoma (SCC) in situ] is rare. The pathogenesis of the disease is linked to human papilloma virus, and in some instances to chronic immunosuppression. The usual management of periungual BD is by local excision, Mohs micrographic surgery or distal phalanx amputation. Our patient was offered radiotherapy in the hope of maximizing residual function and minimizing morbidity from treatment. A good response was seen at 2 months post-radiotherapy, but this was followed by relapses at 4 and 6 months post-radiotherapy. Persistent anonychia resulted in improved access to the involved skin, making topical therapy possible. Radiotherapy can be a valuable management approach for periungual SCC/BD in locations where amputation could result in substantial disability.