Conflict of interest: none declared.
Clinical dermatology ● Concise report
Eosinophilic fasciitis associated with hypereosinophilia, abnormal bone-marrow karyotype and inversion of chromosome 5
Article first published online: 16 NOV 2013
© 2013 British Association of Dermatologists
Clinical and Experimental Dermatology
Volume 39, Issue 2, pages 150–153, March 2014
How to Cite
Ferguson, J. S., Bosworth, J., Min, T., Mercieca, J. and Holden, C. A. (2014), Eosinophilic fasciitis associated with hypereosinophilia, abnormal bone-marrow karyotype and inversion of chromosome 5. Clinical and Experimental Dermatology, 39: 150–153. doi: 10.1111/ced.12228
The first two authors contributed equally to this work and should be considered joint first authors.
- Issue published online: 13 FEB 2014
- Article first published online: 16 NOV 2013
- Manuscript Accepted: 28 MAY 2013
We report the case of a male patient presenting with eosinophilia, pulmonary oedema and eosinophilic fasciitis (EF). He had the classic clinical appearance and magnetic resonance imaging of EF. Cytogenetic analysis of the bone marrow revealed a previously undescribed pericentric inversion of chromosome 5. Overall, the presentation was consistent with a diagnosis of chronic eosinophilic leukaemia, not otherwise specified (CEL-NOS). Dermatologists should consult a haematologist in cases of EF, in order to rule out possible haematological malignancies.