Conflict of interest: the authors declare that they have no conflicts of interest.
Clinical dermatology ● Concise report
Treatment of nodular facial angiofibromas in tuberous sclerosis, using ultrapulse carbon dioxide laser
Article first published online: 29 MAY 2014
© 2014 British Association of Dermatologists
Clinical and Experimental Dermatology
Volume 39, Issue 6, pages 738–740, August 2014
How to Cite
Biondo, G., Greco, S., Mavilia, L. and Mercuri, S. R. (2014), Treatment of nodular facial angiofibromas in tuberous sclerosis, using ultrapulse carbon dioxide laser. Clinical and Experimental Dermatology, 39: 738–740. doi: 10.1111/ced.12327
- Issue published online: 14 JUL 2014
- Article first published online: 29 MAY 2014
- Manuscript Accepted: 14 DEC 2013
Tuberous sclerosis (TS) is a genodermatosis characterized by facial angiofibromas (FAs). These tumours cause aesthetic disfigurement and obstruction of vision, and haemorrhage when traumatized, which can lead to emotional distress and relationship difficulties. We report the case of a 35-year-old patient with extensive TS-associated FAs that were treated with an ultrapulse carbon dioxide laser (UPCDL). UPCDL laser seems to be a easy, useful and convenient tool for the treatment of nodular FAs, which provides good aesthetic results, and a positive response from patients, who report high levels of satisfaction with the results. Minimal recurrence of the tumours occurred during long-term follow-up, and these were successfully treated with UPCDL. It is not yet possible to correct the genetic alterations underlying TS, but UPCDL treatment is a convenient tool to improve the facial appearance of patients with severe FAs.