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cei12106-sup-0001-si.pptx136K

Fig. S1. Interleukin (IL)-1β and IL-6 production in the lungs of severe acute respiratory distress syndrome (ARDS) mice. Mice received intratracheal administration of lipopolysaccharide (LPS) or phosphate-buffered saline (PBS) 24 h after administration of α-galactosylceramide (α-GalCer) or 0·4% dimethylsulphoxide (DMSO)-containing phosphate-buffered saline (dPBS) via the same route. The IL-1-β and IL-6 concentrations in the bronchoalveolar lavage (BAL) fluids were measured at 0, 6, 12 and 24 h after treatment with LPS or PBS. The measurements in BAL fluids are normalized to the respective protein content. The data are shown as the median and interquartiles and each dot represents an individual mouse. *P < 0·05.

cei12106-sup-0002-si.docx26K

Table S1. Effect of recombinant thrombomodulin on interleukin (IL)-1β and IL-6 production in the lungs of severe acute respiratory distress syndrome (ARDS) mice.

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