What is the best approach to the teenage patient presenting with nonclassical Congenital adrenal hyperplasia: should we always treat with glucocorticoids?
Article first published online: 25 JAN 2013
© 2012 Blackwell Publishing Ltd
Volume 78, Issue 3, pages 338–341, March 2013
How to Cite
Matthews, D. and Cheetham, T. (2013), What is the best approach to the teenage patient presenting with nonclassical Congenital adrenal hyperplasia: should we always treat with glucocorticoids?. Clinical Endocrinology, 78: 338–341. doi: 10.1111/cen.12065
- Issue published online: 25 JAN 2013
- Article first published online: 25 JAN 2013
- Accepted manuscript online: 7 OCT 2012 11:03PM EST
- Manuscript Accepted: 2 OCT 2012
- Manuscript Revised: 25 SEP 2012
- Manuscript Revised: 24 JUL 2012
- Manuscript Received: 25 JUN 2012
Patients with Congenital adrenal hyperplasia due to partial deficiency in the enzyme 21-hydroxlyase can present in childhood or adolescence with signs of adrenal androgen excess. Strategies to reduce the impact of androgen excess in females include cosmetic measures as well as antiandrogens and agents such as the combined oral contraceptive pill. Glucocorticoid may not be appropriate straightaway but can be introduced if other measures are ineffective or when pregnancy is planned.