Nothing to declare.
Integrating next-generation sequencing into the diagnostic testing of inherited cancer predisposition
Article first published online: 29 OCT 2012
© 2012 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd
Volume 83, Issue 1, pages 2–6, January 2013
How to Cite
Integrating next-generation sequencing into the diagnostic testing of inherited cancer predisposition., , , .
- Issue published online: 17 DEC 2012
- Article first published online: 29 OCT 2012
- Accepted manuscript online: 28 SEP 2012 11:50AM EST
- Manuscript Revised: 25 SEP 2012
- Manuscript Accepted: 25 SEP 2012
- Manuscript Received: 13 AUG 2012
- hereditary cancer;
- next-generation sequencing
The clinical application of next-generation sequencing (NGS) as a diagnostic tool has become increasingly evident. The coupling of NGS technologies with new genomic sequence enrichment methods has made the sequencing of panels of target genes technically feasible, at the same time as making such an approach cost-effective for diagnostic applications. In this article, we discuss recent studies that have applied NGS in the diagnostic setting in relation to hereditary cancer.