Dr Hoover-Fong receives consultative funding from BioMarin for study development related to achondroplasia.
Cross-sectional assessment of pain and physical function in skeletal dysplasia patients
Article first published online: 29 NOV 2012
© 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Volume 84, Issue 3, pages 237–243, September 2013
How to Cite
Cross-sectional assessment of pain and physical function in skeletal dysplasia patients., , , , , , , .
- Issue published online: 12 AUG 2013
- Article first published online: 29 NOV 2012
- Accepted manuscript online: 25 OCT 2012 08:20AM EST
- Manuscript Revised: 22 OCT 2012
- Manuscript Accepted: 22 OCT 2012
- Manuscript Received: 6 AUG 2012
- Alan and Kathryn Greenberg Center for Skeletal Dysplasias
- skeletal dysplasia
Short stature skeletal dysplasia (SD) patients have orthopedic and neurologic complications causing significant pain and physical disability. We conducted a large cross-sectional online survey in 361 people with short stature SD (>10 years) to describe pain prevalence, characteristics, and the relationship between pain and function. Chronic pain prevalence per Brief Pain Inventory (BPI) was 70.3%. Women reported more pain than men (73% vs 63% p = 0.04). Pain Severity Score (average of current, worst, least and average pain) averaged 3.3 ± 2, while the Pain Interference Score (with daily activities) averaged 3.4 ± 2.7 on a 10-point scale. Per Bleck scale, 20.5% had little or no functional capacity. Increasing age and decreased ambulation independently predicted chronic pain. Chronic pain is prevalent in short stature SD patients and associated with poor physical function. Further study is required to clarify the temporal relationship among pain, function and treatments.