The authors declare no conflict of interest.
The utilization of pre-implantation genetic testing in the absence of governance: a real-time experience
Article first published online: 2 SEP 2013
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Volume 86, Issue 2, pages 177–180, August 2014
How to Cite
Farra, C., Nassar, A., Arawi, T., Ashkar, H., Monsef, C. and Awwad, J. (2014), The utilization of pre-implantation genetic testing in the absence of governance: a real-time experience. Clinical Genetics, 86: 177–180. doi: 10.1111/cge.12250
- Issue published online: 21 JUL 2014
- Article first published online: 2 SEP 2013
- Accepted manuscript online: 12 AUG 2013 06:11AM EST
- Manuscript Accepted: 6 AUG 2013
- Manuscript Revised: 5 AUG 2013
- Manuscript Received: 23 MAY 2013
- gender selection;
- pre-implantation genetic testing;
To create a diagnostic document describing the utilization of pre-implantation genetic testing (PGT) in the absence of monitoring and regulation. Retrospective cohort study of couples undergoing PGT between 2004 and 2007 in Lebanon. The clinical indications for 192 PGT cycles performed during the study period were gender selection (96.3%), chromosomal aneuploidy (3.1%), and balanced translocation (0.5%). When gender selection was sought, the selection of a son was desired in 94.1% of cases. Of couples undergoing PGT for sex selection, 16.2% were childless, 8.6% had one child of the opposite gender, 28.1% had two same-gender children, 29.7% had three same-gender children, and 11.9% had four or more. Our findings demonstrate the morally questionable consequences of self-regulated systems in which physicians are the sole gatekeepers of norms and ethics.