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Keywords:

  • Cardiac Malformation Incidence;
  • Hispanics;
  • Total Anomalous Pulmonary Venous Connection;
  • Amerindian Genetics

Abstract

Objective

Ethnicity may influence the occurrence of specific cardiac malformations.

Design

We retrospectively analyzed the occurrence of isolated total anomalous pulmonary venous connection in the Hispanic and non-Hispanic populations of Southern Nevada over a 10-year period from 2003 to 2013.

Results

The mean cases per 100 000 live births among Hispanics was 19.8 (99% confidence interval 5.9–33.7) and among non-Hispanics was 2.5 (99% confidence interval 0.4–4.6), P = 0.007.

Conclusions

We found a significantly higher incidence of isolated total anomalous pulmonary venous connection in Hispanics vs. non-Hispanics.