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An Increased Incidence of Total Anomalous Pulmonary Venous Connection among Hispanics in Southern Nevada

Authors

  • William N. Evans MD,

    Corresponding author
    1. Pediatric Cardiology Division, Children's Heart Center, Las Vegas, Nev, USA
    2. School of Medicine, Department of Pediatrics, Division of Cardiology, University of Nevada, Las Vegas, Nev, USA
    • Corresponding Author: William N. Evans MD, FACC, Children's Heart Center, 3006 S. Maryland Pkwy, Ste. 690, Las Vegas, NV 89109, USA. Tel: (702) 732-1290; Fax: (702) 732-1385; E-mail: wnevans50@aol.com

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  • Ruben J. Acherman MD,

    1. Pediatric Cardiology Division, Children's Heart Center, Las Vegas, Nev, USA
    2. School of Medicine, Department of Pediatrics, Division of Cardiology, University of Nevada, Las Vegas, Nev, USA
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  • Michael L. Ciccolo MD,

    1. Congenital Cardiothoracic Surgery Division, Children's Heart Center, Las Vegas, Nev, USA
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  • William J. Castillo MD,

    1. Pediatric Cardiology Division, Children's Heart Center, Las Vegas, Nev, USA
    2. School of Medicine, Department of Pediatrics, Division of Cardiology, University of Nevada, Las Vegas, Nev, USA
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  • Humberto Restrepo MD, MPH

    1. Pediatric Cardiology Division, Children's Heart Center, Las Vegas, Nev, USA
    2. School of Medicine, Department of Pediatrics, Division of Cardiology, University of Nevada, Las Vegas, Nev, USA
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  • Financial Support: This study was self-funded by the Children's Heart Center Nevada and not supported by grants from any agency either commercial or not for profit.

Abstract

Objective

Ethnicity may influence the occurrence of specific cardiac malformations.

Design

We retrospectively analyzed the occurrence of isolated total anomalous pulmonary venous connection in the Hispanic and non-Hispanic populations of Southern Nevada over a 10-year period from 2003 to 2013.

Results

The mean cases per 100 000 live births among Hispanics was 19.8 (99% confidence interval 5.9–33.7) and among non-Hispanics was 2.5 (99% confidence interval 0.4–4.6), P = 0.007.

Conclusions

We found a significantly higher incidence of isolated total anomalous pulmonary venous connection in Hispanics vs. non-Hispanics.

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