• bone graft;
  • collagen membrane;
  • connective tissue;
  • implantoplasty;
  • peri-implantitis;
  • surgical regenerative therapy



Mucosal recessions are a common finding following surgical treatment of peri-implantitis, thus compromising the overall esthetic outcome of implant therapy. This case series aimed at evaluating the clinical outcome of a combined surgical therapy of advanced peri-implantitis lesions with concomitant soft tissue volume augmentation.

Material and methods

Ten patients (n = 13 implants exhibiting combined supra- and intrabony defects) underwent access flap surgery, implantoplasty at bucally and supracrestally exposed implant parts, and augmentation of the intrabony components using a natural bone mineral and a native collagen membrane after surface decontamination. A subepithelial connective tissue graft was harvested from the palate and adapted to the wound area to support transmucosal healing. Clinical parameters (i.e. bleeding on probing – BOP; probing depths – PD; mucosal recession – MR; clinical attachment level – CAL) were recorded at baseline and after 6 months.


At 6 months, the combined surgical procedure was associated with a significant reduction in mean BOP (74.39 ± 28.52%), PD (2.53 ± 1.80 mm), and CAL (2.07 ± 1.93 mm) values. Site-level analysis has pointed to a slight increase in mean mucosal height (0.07 ± 0.5 mm) at the buccal aspects (i.e. mb, b, db).


The combined surgical procedure investigated may be effective in controlling advanced peri-implantitis lesions without compromising the overall esthetic outcome in the short term.