Lipid interactions during virus entry and infection
Article first published online: 11 SEP 2014
© 2014 The Authors. Cellular Microbiology published by John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 16, Issue 10, pages 1493–1502, October 2014
How to Cite
Mazzon, M. and Mercer, J. (2014), Lipid interactions during virus entry and infection. Cellular Microbiology, 16: 1493–1502. doi: 10.1111/cmi.12340
- Issue published online: 17 SEP 2014
- Article first published online: 11 SEP 2014
- Accepted manuscript online: 6 AUG 2014 10:33PM EST
- Manuscript Accepted: 1 AUG 2014
- Manuscript Revised: 26 JUL 2014
- Manuscript Received: 24 JUN 2014
- MRC Laboratory for Molecular Cell Biology, University College London
For entry and infection viruses have developed numerous strategies to subjugate indispensable cellular factors and functions. Host cell lipids and cellular lipid synthesis machinery are no exception. Not only do viruses exploit existing lipid signalling and modifications for virus entry and trafficking, they also reprogram lipid synthesis, metabolism, and compartmentalization for assembly and egress. Here we review these various concepts and highlight recent progress in understanding viral interactions with host cell lipids during entry and assembly.