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Cellular Microbiology

Cover image for Vol. 14 Issue 4

April 2012

Volume 14, Issue 4

Pages i–i, 447–607

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Editors' Choice
    4. Thematic Reviews – Host Responses to Pathogens
    5. Original articles
    1. You have free access to this content
      Issue Information (page i)

      Version of Record online: 12 MAR 2012 | DOI: 10.1111/j.1462-5822.2012.01782.x

  2. Editors' Choice

    1. Top of page
    2. Issue Information
    3. Editors' Choice
    4. Thematic Reviews – Host Responses to Pathogens
    5. Original articles
    1. You have free access to this content
      Escherichia coli-induced epithelial hyporesponsiveness to secretagogues is associated with altered CFTR localization (pages 447–459)

      Christina L. Ohland, Rebekah DeVinney and Wallace K. MacNaughton

      Version of Record online: 8 FEB 2012 | DOI: 10.1111/j.1462-5822.2011.01744.x

      Thumbnail image of graphical abstract

      Intestinal epithelial cells secrete chloride and bicarbonate ions through the CFTR channel in order to drive a local fluid flux that prevents bacterial attachment. We have shown that enteropathogenic E. coli (EPEC) can down-regulate this apically driven ion flux by triggering an EspA,B,D-dependent internalization of CFTR, without affecting either cAMP-mediated regulation of the channel or basolateral ion channels (denoted by red “X”s). Our results suggest a mechanism whereby pathogenic E. coli may suppress the secretory component of intestinal epithelial host defence

  3. Thematic Reviews – Host Responses to Pathogens

    1. Top of page
    2. Issue Information
    3. Editors' Choice
    4. Thematic Reviews – Host Responses to Pathogens
    5. Original articles
    1. Microreviews

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      Recognition of Streptococcus pneumoniae by the innate immune system (pages 460–466)

      Uwe Koppe, Norbert Suttorp and Bastian Opitz

      Version of Record online: 8 FEB 2012 | DOI: 10.1111/j.1462-5822.2011.01746.x

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      Molecular view on PRR cross-talk in antifungal immunity (pages 467–474)

      S. Hontelez, A. Sanecka, M. G. Netea, A. B. van Spriel and G. J. Adema

      Version of Record online: 14 FEB 2012 | DOI: 10.1111/j.1462-5822.2012.01748.x

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      Innate host responses to enteric bacterial pathogens: a balancing act between resistance and tolerance (pages 475–484)

      Kirk S. Bergstrom, Ho Pan Sham, Maryam Zarepour and Bruce A. Vallance

      Version of Record online: 15 FEB 2012 | DOI: 10.1111/j.1462-5822.2012.01750.x

  4. Original articles

    1. Top of page
    2. Issue Information
    3. Editors' Choice
    4. Thematic Reviews – Host Responses to Pathogens
    5. Original articles
    1. You have free access to this content
      Salmonella type III effector SpvC, a phosphothreonine lyase, contributes to reduction in inflammatory response during intestinal phase of infection (pages 485–499)

      Takeshi Haneda, Yuta Ishii, Hiromichi Shimizu, Keiko Ohshima, Naoyuki Iida, Hirofumi Danbara and Nobuhiko Okada

      Version of Record online: 18 JAN 2012 | DOI: 10.1111/j.1462-5822.2011.01733.x

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      Methylation of glycosylated sphingolipid modulates membrane lipid topography and pathogenicity of Cryptococcus neoformans (pages 500–516)

      Arpita Singh, Haitao Wang, Liana C. Silva, Chongzheng Na, Manuel Prieto, Anthony H. Futerman, Chiara Luberto and Maurizio Del Poeta

      Version of Record online: 9 JAN 2012 | DOI: 10.1111/j.1462-5822.2011.01735.x

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      Distinct signalling mechanisms mediate neutrophil attraction to bacterial infection and tissue injury (pages 517–528)

      Qing Deng, Elizabeth A. Harvie and Anna Huttenlocher

      Version of Record online: 16 JAN 2012 | DOI: 10.1111/j.1462-5822.2011.01738.x

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      Subversion of NPC1 pathway of cholesterol transport by Anaplasma phagocytophilum (pages 560–576)

      Qingming Xiong and Yasuko Rikihisa

      Version of Record online: 8 FEB 2012 | DOI: 10.1111/j.1462-5822.2011.01742.x

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      Porphyromonas gingivalis SerB-mediated dephosphorylation of host cell cofilin modulates invasion efficiency (pages 577–588)

      Catherine E. Moffatt, Hiroaki Inaba, Takanori Hirano and Richard J. Lamont

      Version of Record online: 2 FEB 2012 | DOI: 10.1111/j.1462-5822.2011.01743.x

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      Autophagy is a cell death mechanism in Toxoplasma gondii (pages 589–607)

      Debasish Ghosh, Julia L. Walton, Paul D. Roepe and Anthony P. Sinai

      Version of Record online: 8 FEB 2012 | DOI: 10.1111/j.1462-5822.2011.01745.x

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